SuperiorMuscle.com - Bodybuilding Forums
Register Members Search Today's Posts Mark Forums Read

Go Back   SuperiorMuscle.com - Bodybuilding Forums > Superior Fitness Section > Anabolic Steroids
Reload this Page "Cleaning out the receptors"

Anabolic Steroids Steroids, GH, PEDs, & Peptides Discussion


Like Tree9Likes

Reply
 
LinkBack Thread Tools
Old 07-20-04, 07:48 PM
"Cleaning out the receptors"
  #1
 
Superior Newbie
Join Date: Jul 2004
Age: 43
Likes: 0
Can someone explain exactly what this means, and how to go about doing it properly? I have heard the receptors get 'filled up' and inhibit gains. What are the receptors?

If this is a stupid question just point me in the direction of some decent information. Thanks in advance.
is Offline   Reply With Quote

Old 07-20-04, 09:14 PM
  #2
 
Superior Newbie
Join Date: Jul 2004
Age: 43
Likes: 0
No answers????

Come on guys... There are more people on this board than most that I've been to and nobody can give me an answer or point me in the right direction to find it myself? I'll have to continue searching. Thanks.
is Offline   Reply With Quote
Old 07-20-04, 09:25 PM
  #3
 
Superior Newbie
Join Date: Feb 2004
Likes: 0
I have never heard of "cleaning out" receptor sites. But, that doesn't mean it is not possible. Just like every chemical system in your body, hormones have receptor sites. They are designed to only accept things with a certain chemical or molecular make up. This makes it so nerve impulses and hormone reactions don't get mixed up. I DO know that receptor sites can become desensitized over time, but I don't know of any way to reverse this. I'm sure Skyefire can explain this much better. You can take a look at most anatomy or chemistry textbooks for a more in depth description....it shouldn't be hard to find. I hope this helped a little bit!
is Offline   Reply With Quote
Old 07-20-04, 09:26 PM
  #4
 
Bouncer's Avatar
 
Administrator
Join Date: Jul 2003
Location: California
Likes: 5398
The receptor theory has been proven bunk. We have millions of new receptors every minute.
is Online   Reply With Quote
Old 07-20-04, 09:27 PM
  #5
 
Superior Newbie
Join Date: Jul 2004
Age: 43
Likes: 0
For those who might not know about receptors....
I found this at Intense-Training.com

Cleaning Receptors

--------------------------------------------------------------------------------

Written by Trevor Smith.
I do not necessarily agree with the product plug at the end and would also offer up Clen as a viable alternative to DNP or T3
~~~~~~~~~


A lot has been said in regards to clearing the receptors and I thought now would be a good time to delve into this
subject and simplify things.

Basically, one must view the receptor sites as parking spaces.

Envision a slew of parking spaces that are all empty. Now we are going to call these parking spaces your receptor
sites and we shall call steroids the cars. Now I want you to imagine one of those old 1950's style drive up
hamburger stands where the girls come up in roller skates and take your order. Typically one would order a burger,
fries and a coke--ah the food of the gods--the waitress would take the order, go bring the information to the
cook, who would in-turn make the food and the waitress would then bring the food to you and you would then
begin eating which is the whole reason you came to the hamburger stand in the first place.

I think everyone can easily understand that. Which means everyone can easily understand all they need to know
about the receptor sites because they do the exact same thing. We will keep with this hamburger stand model and
explain what happens when you inject steroids and they begin to go to work.

Remember how I said steroids were like the cars and the parking spaces were like the receptor sites? Well it is
basically that simple. When you inject testosterone or any one of it's anabolic or androgenic derivatives, you are
sending a whole slew of "cars" into your system. Now these "cars" are on a mission--just like you would be if you
were hungry and heading to a hamburger stand. They have orders to place with the cells, but before they can
place them they must first find a parking space.

Now let's say you have never used steroids before. If this were the case, it would be very much like a hamburger
stand that was having a grand opening....lots and lots of empty parking spaces waiting for cars to fill them up and
place their orders. The steroids (cars) enter the system and come to a brand new hamburger stand called your
cells. Now these cells have never previously been open to the boat-load of anabolics that are now present in the
system because they previously only dealt with what your body naturally produced. However, there are lots of
extra parking spaces that can be utilized and so the steroids park themselves into these spaces.

Once they are parked a "waitress" called CYCLICl AMP literally crosses the cellular membrane which is totally
impenetrably to anything else and takes the order from the steroid. The order is quite simple: Build More Muscle!!

The "waitress" then crosses back through the cellular membrane and brings the order to the "cook" called the
Nucleus who begins to fill it by ordering its helpers called Ribosomes to produce muscle protein.. Now different
steroids will have slightly different orders in that some may have a bigger order for the cook to fill--such as
testosterone. The thing you have to realize is that a lot of times, after the order is placed, the steroid does not
necessarily leave the parking space and make it available to other steroids.....it will often sit in the parking space
even though it is no longer sending orders to the "waitress" to bring to the "cook", and this is where the problem of
"DOWN-REGULATION" comes in. You see even if you send in more and more fresh new "cars" to occupy the
receptor spaces, if they are already taken up by old "dead cars" you are **** out of luck.....

This is why you do not continually grow by injecting bigger and bigger doses of steroids. THERE ARE A LIMITED
NUMBER OF PARKING SPACES. Now it would not be so bad if all the parking spaces were taken by "cars" that were
sending orders to the cook, because that is when you grow. The problem is when there are "cars" that are no
longer sending orders and on top of that have dead batteries which is preventing them from exiting the receptors
parking space.

This is what the whole point of this article is....TOWING AWAY ALL THE DEAD "CARS" FROM THE RECEPTOR SITES
PARKING SPACES AS TO FREE THEM UP FOR NEW, FRESH, HUNGRY "CARS" TO OCCUPY THEM...This will result in
new muscle mass!

O.K. Trevor, I am with you so far, but what the **** can I do about it?

The answer is ...PLENTY!

First and foremost, is to plan sensible courses. This is why I am an advocate of short courses designed in such a
fashion as to have all drugs out of the system by the end of the cycle and then allow for a 3-4 week off time in
which you are totally clean. If you stay on these monster 4-6 month courses, you just wind up screwing yourself
and requiring that much longer of an off period. The longer you are on, the more the body recognizes that there is
"too much" in the system and will begin to take counter measures. And the longer you are on, the more "dead cars"
you will have sitting in the receptor parking spaces which means NO MORE GROWING!

Now with this in mind, how can we help get the cars out of there?

Well WE actually cannot, but the body can and will. Basically as time goes by, the body will free up the parking
spaces just like a tow truck would remove a dead car from a parking space. However, you are at the mercy of time
in this situation which is why it is important to utilize short courses that will cause less disturbance in the system,
less "dead cars" in the receptor spaces and therefore less time needed for the body to remove them and free up
the spaces.

That being said, it should be noted that even short course will pile up "dead cars" after a while and you should give
yourself an extended clean out of 2 months at least once a year.

But Trevor, isn't there anything I can do to help speed the process?

Once again the answer is yes!

You can help speed the process up dramatically by increasing your metabolic rate...Speeding up the metabolic rate
is akin to hiring extra tow trucks to clear out all those "dead cars" that are occupying the receptor sites!

Have you ever know a person who was much, much fatter than you and yet ate half as much?

These poor bastards think they were given the genetic shaft and try every diet fad imaginable only to stay fat.
Their problem no longer lies in their eating habits--which is ironic--; it lies in their metabolism, which basically was
shut down due to the excess eating and lack of exercise that got them fat in the first place. Once you understand
this, you can easily control your weight for the rest of your life. But what the **** does this have to due with
steroid receptor sites?

EVERYTHING!

The same thing I would prescribe someone whose metabolism has shut down due to obesity, is the same thing I
would prescribe someone who's receptor sites are all clogged and is no longer making progress....INCREASE THE
METABOLIC RATE!!

Below I will outline a few ways this can be achieved in the constraints of a 4 week Receptor Clearing Cycle follwing
the completion of a Muscle Building Course using anabolics:

Diet: I suggest cutting back 300 calories below maintenance per day during a 4 week off time from your anabolic
regime...I also suggest eating 6-8 small meals spread out from early morning to late at night. The higher the
number of meals you eat, the more your body has to go to work and break down the food which causes the
metabolic rate to increase.

Aerobics: Yet another tool in the battle to increase the metabolism, I would suggest low level aerobics 5 times per
week 30 minutes per session.

Pharmacology: It is important that one does not have ANY anabolics that are active in the system during this time
period.....make sure that you have had a good 4 weeks since your last shot of long acting compound before you
embark on this 4 week receptor clearing cycle....otherwise you are wasting your ****ing time! That being said, I
would suggest the use of the following compounds to help accelerate the Receptor Clearing Process:

1. D.N.P. -- Understand that this is a ****ing vicious poison and a component in T.N.T., and I do not suggest it's
use at all, but to be fair I must admit that NOTHING can raise the metabolic rate like D.N.P. can. Because this is
well known, there are many people that will want to try it...This being the case, D.N.P. should only be used in the
following manner during this course: 3 days on, 4 days off at a dose of 4mg per kilogram of bodyweight taken
before bed----have plenty of towels around and a fan to keep you cool!
2. Cytomel--T3 is another booster of metabolic rate which is why the fitness models live on this stuff...it keeps
you engines running high and burns the fat right off....In this case, we are more concerned with the fact that it
increases the metabolic rate. Suggested use is 75mcg -100mcg 5 days on 2 days off for the 4 week course

3. B.M.R. 10--I know, I know shameless plug right...well I don't care, in the past 3 weeks since this product has
been released I have people calling me and emailing me telling me that this product blows the doors off every other
thermogenic including, E/C/A, Clenbuterol and Cytomel, and Tenuate.....People actually think I put D.N.P. in this
product. Trust me I did not, but I did formulate a product with 11 Basil Metabolic Rate increasing compounds that
will make you hotter than an oven and melt the fat right off you. Again in this course we are more concerned with
the metabolic increase this product will cause. Why hasn't anyone else come up with this formula...#1 All the other
companies market to the general public which causes them water down there products #2 it is too expensive for
their profit minded companies to justify it's production #3 They are not bodybuilders, I am and I know what works
and what doesn not.

Doses: On the days you are NOT using D.N.P. have 4 caps before each of the first 5 meals.

* If you do not wish to use D.N.P.---which I think is the smarter approach as it is very dangerous---you can
simply use the B.M.R. 10 on the days that you would be using D.N.P. In my opinion this is smarter, safer and will be
just as effective.

There you have it...a brief simple lesson on your receptors and how you might go about keeping them free and
clear so you can continue to Grow, Grow, Grow
is Offline   Reply With Quote
Old 07-20-04, 09:31 PM
  #6
 
Superior Pro
Join Date: Jul 2003
Location: new york
Age: 46
Likes: 0
Androgen receptors have been shown to up-regulate in response to administration of exogenous androgens. Thereís no such thing as "plugging up" or "cleaning out" a receptor. Itís a matter of increasing (up-regulating) or decreasing (down-regulating) androgen receptor expression and, going further upstream, increasing or decreasing AR mRNA expression.
is Offline   Reply With Quote
Old 07-20-04, 09:37 PM
  #7
 
Superior Newbie
Join Date: Jul 2004
Age: 43
Likes: 0
Quote:
Originally posted by THE BOUNCER
The receptor theory has been proven bunk. We have millions of new receptors every minute.
So it is unneccessary to 'clean the receptors'? Would normal PCT followed by a determined "OFF" time be adequate then?
is Offline   Reply With Quote
Old 07-20-04, 09:38 PM
  #8
 
Bouncer's Avatar
 
Administrator
Join Date: Jul 2003
Location: California
Likes: 5398
Quote:
Originally posted by house1
Androgen receptors have been shown to up-regulate in response to administration of exogenous androgens. Thereís no such thing as "plugging up" or "cleaning out" a receptor. Itís a matter of increasing (up-regulating) or decreasing (down-regulating) androgen receptor expression and, going further upstream, increasing or decreasing AR mRNA expression.
exactlly. the body simply needs more to grow.
is Online   Reply With Quote
Old 07-20-04, 09:39 PM
  #9
 
Superior Newbie
Join Date: Jul 2004
Age: 43
Likes: 0
Also, is Clen okay to use during PCT? or between cycles?
is Offline   Reply With Quote
Old 07-20-04, 09:40 PM
  #10
 
Bouncer's Avatar
 
Administrator
Join Date: Jul 2003
Location: California
Likes: 5398
Quote:
Originally posted by RollPlayer
So it is unneccessary to 'clean the receptors'? Would normal PCT followed by a determined "OFF" time be adequate then?
You cant clean a receptor so to speak. your body will eventually just stop growing on 500mgs of test. no matter what you try to do to the receptors, your body wont grow until you up the dose a bit.
is Online   Reply With Quote
Old 07-20-04, 09:42 PM
  #11
 
Superior Newbie
Join Date: Jul 2004
Age: 43
Likes: 0
Thanks guys. I'm heading into PCT after my first cycle and was just curious. Appreciated.
is Offline   Reply With Quote
Old 07-20-04, 11:02 PM
  #12
 
canadagold's Avatar
 
Superior Amateur
Join Date: Aug 2003
Location: Canada
Likes: 0
I think with Trevors analogy he should have put in that when a restaurant gets so busy that it can't hold all the cars the owner will then buy more parking spaces so that more cars can park. . .or in other words more receptors proliferate and therefore more androgens can be taken to fill them and that equals more growth. . .
is Offline   Reply With Quote
Old 07-21-04, 12:00 AM
  #13
 
Superior Newbie
Join Date: Jul 2004
Likes: 0
Rollplayer you're not too far off. If everyone that disputes rollplayer's first post would simply read the first twenty pages of BTPB you'd have a much greater understanding that receptors can not only be cleaned out but at a much faster rate than letting the body naturally cleanse itself. This is not only backed up in the book, the book also has a complete works sited/bibliograpy which posts the exact scientific article. Of course the example in the book may kill a normal human, there are safer ways to accomplish it now. If you'd like to post any rebuttles or arguments which I can sense coming from the posts I've read above, please read the first part of the book before taking a solid stance and flaming the shit out of me.
is Offline   Reply With Quote
Old 05-23-16, 11:46 AM
Unhappy Uuugeboy
  #14
 
Superior Newbie
Join Date: May 2016
Likes: 0
Hi Uuugeboy I have totally screwed myself abusing steroids over the years I havnt been able to keep a pound of it am and half a stone below my usual weight now and steroids don't have any affect on me what so ever now, you say I can sort out my receptors faster than once thought, how would you recommend I do this? And have you seen first hand this route work for other people before? Thanks
is Offline   Reply With Quote
Old 05-23-16, 02:02 PM
  #15
 
Bouncer's Avatar
 
Administrator
Join Date: Jul 2003
Location: California
Likes: 5398
Quote:
Originally Posted by thedon768 View Post
Hi Uuugeboy I have totally screwed myself abusing steroids over the years I havnt been able to keep a pound of it am and half a stone below my usual weight now and steroids don't have any affect on me what so ever now, you say I can sort out my receptors faster than once thought, how would you recommend I do this? And have you seen first hand this route work for other people before? Thanks
Your gear is either fake or you need to up the dose. Train heavy and hard, feed your muscles quality cals and you'll get results. May need to switch things up. Different compounds etc.. Switch from long acting test to short acting test, add compounds, remove compounds, mix things up bro.

If you've been on on 500mgs test e for 10 years your not gonna get any new results.
jack tors likes this.
is Online   Reply With Quote
Old 05-23-16, 04:05 PM
  #16
 
StanG's Avatar
 
Superior Amateur
Join Date: Aug 2012
Likes: 122
That whole intense training article is BS and packed with misinformation. The whole parking space analogy is a bad one. It implies that there are a set number of spots (or receptors) and that they last forever etc..
The fact is the number of receptors is constantly changing and also as has been stated in the presence of excess androgens the body generates new & more receptors. Also of note the receptor life is only about 3 hours. They are constantly dying and being generated. It is also important to note that in the presence of excess androgen not only does the number of receptors increase but the lifespan of said receptors nearly doubles to 6 hrs.
There is no cleaning of receptors and so on as the guys have pointed out.
Bouncer likes this.
is Online   Reply With Quote
Old 05-23-16, 04:40 PM
  #17
 
Mr I's Avatar
 
Founding Member
Join Date: Nov 2004
Location: Self Righteous Brit
Likes: 1241
See below
Attached Images
File Type: jpg 13238900_999478930171381_7360511639894534560_n.jpg (35.6 KB, 11 views)
Bouncer likes this.
is Online   Reply With Quote
Old 05-23-16, 04:42 PM
  #18
 
Mr I's Avatar
 
Founding Member
Join Date: Nov 2004
Location: Self Righteous Brit
Likes: 1241
Can someone show me a picture of a receptor please?
Bouncer likes this.
is Online   Reply With Quote
Old 05-23-16, 05:12 PM
  #19
 
Bouncer's Avatar
 
Administrator
Join Date: Jul 2003
Location: California
Likes: 5398


is Online   Reply With Quote
Old 05-23-16, 11:30 PM
  #20
 
Mr I's Avatar
 
Founding Member
Join Date: Nov 2004
Location: Self Righteous Brit
Likes: 1241
^ That's a cartoon

Doctors and scientists have pictures magnified if neccassary of every legit body part, I want to see one of a receptor
is Online   Reply With Quote
Old 05-24-16, 06:49 AM
  #21
 
Bouncer's Avatar
 
Administrator
Join Date: Jul 2003
Location: California
Likes: 5398
No I agree. The accepted bro science theory about androgen receptors getting "burnt out" has always been one of those things people just accepted.
Mr I likes this.
is Online   Reply With Quote
Old 05-24-16, 09:16 AM
  #22
 
Superior Newbie
Join Date: May 2016
Likes: 0
thanks for reply bouncer, well the thing is i dont even get water retention from my gear any more, its real i know for a fact it is, but doesnt matter how much i take it doesnt seem to work, parts of the day i look fuller and i might put a few pounds on over night then a day later my gains have disapreaed its not normal it really isnt can you think of what else it might be bro?
is Offline   Reply With Quote
Old 05-24-16, 09:34 AM
  #23
 
Bouncer's Avatar
 
Administrator
Join Date: Jul 2003
Location: California
Likes: 5398
Quote:
Originally Posted by thedon768 View Post
thanks for reply bouncer, well the thing is i dont even get water retention from my gear any more, its real i know for a fact it is, but doesnt matter how much i take it doesnt seem to work, parts of the day i look fuller and i might put a few pounds on over night then a day later my gains have disapreaed its not normal it really isnt can you think of what else it might be bro?
What is your dosing and which AAS are you running? How long have you been running them for?

If your AAS are real and you know it as a fact and your actually losing weight the only thing I can think of is that your either not getting enough cals or your overtraining.
is Online   Reply With Quote
Old 05-24-16, 09:38 AM
  #24
 
Superior Newbie
Join Date: May 2016
Likes: 0
seriously bouncer its none of the above 5000 kals a daye always worked for me in the past and i defintely dont over train, wtf is wrong with me lol
is Offline   Reply With Quote
Old 05-24-16, 09:41 AM
  #25
 
Superior Newbie
Join Date: May 2016
Likes: 0
i am using 3 ml a week test 400 and i started 1 ml every other day with prop and 5 dbol dail and not a thing has changed
is Offline   Reply With Quote
Old 05-24-16, 09:44 AM
  #26
 
epix00's Avatar
 
Founding Member
Join Date: Jul 2004
Likes: 200
If your steroids are real and you are truly eating what you say you are then something is definitely wrong. It could be something like an intestinal parasite that is taking the nutrients from your food instead of going into your body or something else way more complex.

I honestly wouldn't think its something like this and I would personally assume your steroids are fake. If they are not fake and you are absolutely positive...it might be something else a little more serious.
is Online   Reply With Quote
Old 05-24-16, 09:46 AM
  #27
 
Mr I's Avatar
 
Founding Member
Join Date: Nov 2004
Location: Self Righteous Brit
Likes: 1241
Thedon, if you're losing weight on all that and your not over 300 lb now or mega stressed or in amphetamines. You need to see your doctor because something else in your body is sucking the calories out.
is Online   Reply With Quote
Old 05-24-16, 09:59 AM
  #28
 
Bouncer's Avatar
 
Administrator
Join Date: Jul 2003
Location: California
Likes: 5398
Yea something is wrong bro. Real Steroids at those doses and 5k calories should not ever equal losing weight and getting weaker.

Not to scare you but I'd get blood work. Kidney/liver issues possible, some sort of disease etc..
is Online   Reply With Quote
Old 05-24-16, 10:01 AM
  #29
 
Superior Newbie
Join Date: May 2016
Likes: 0
shit ! ha il get to the docs then, i went through the worst break up of my life just before this all happened more stress than ive ever experienced lol could that be playing a part?
is Offline   Reply With Quote
Old 05-24-16, 10:03 AM
  #30
 
Bouncer's Avatar
 
Administrator
Join Date: Jul 2003
Location: California
Likes: 5398
Stress can play a role yea but the drugs should be overcoming all that. 5 dbol a day a no water retention is strange bro. Would you bet your life the gear is real?
is Online   Reply With Quote
Old 05-24-16, 10:17 AM
  #31
 
Superior Newbie
Join Date: May 2016
Likes: 0
1 million percent gear is real bro
is Offline   Reply With Quote
Old 05-24-16, 10:18 AM
  #32
 
epix00's Avatar
 
Founding Member
Join Date: Jul 2004
Likes: 200
Quote:
Originally Posted by thedon768 View Post
1 million percent gear is real bro
go to the dr then.
is Online   Reply With Quote
Old 05-24-16, 10:19 AM
  #33
 
Bouncer's Avatar
 
Administrator
Join Date: Jul 2003
Location: California
Likes: 5398
Well then brother, I think it's safe to say with certainty that something is wrong with your health. Is aids a possibility? Lol
epix00 likes this.
is Online   Reply With Quote
Old 05-24-16, 10:20 AM
  #34
 
epix00's Avatar
 
Founding Member
Join Date: Jul 2004
Likes: 200
Quote:
Originally Posted by Bouncer View Post
Well then brother, I think it's safe to say with certainty that something is wrong with your health. Is aids a possibility? Lol
This should not of made me laugh as much as it did.
Bouncer likes this.
is Online   Reply With Quote
Old 05-24-16, 10:56 AM
  #35
 
Superior Newbie
Join Date: May 2016
Likes: 0
hahaha no deffo not, anything else?
is Offline   Reply With Quote
Old 05-24-16, 10:58 AM
  #36
 
Bouncer's Avatar
 
Administrator
Join Date: Jul 2003
Location: California
Likes: 5398
If gear is good and you've been on for years including orals I'm guessing possible kidney issue. Piss dark?
is Online   Reply With Quote
Old 05-24-16, 10:58 AM
  #37
 
Superior Newbie
Join Date: May 2016
Likes: 0
im not losing anymore weight, i am below weight because my t levels are shot ED when im not on gear so all it is is the test isnt working if that makes sense lol
is Offline   Reply With Quote
Old 05-24-16, 10:59 AM
  #38
 
Superior Newbie
Join Date: May 2016
Likes: 0
sometimes can be dark...
is Offline   Reply With Quote
Old 05-24-16, 11:00 AM
  #39
 
Superior Newbie
Join Date: May 2016
Likes: 0
no pain or any effects that might indicate kidney problems but bro i have most certainly smashed my body alongside the gear with drink and drugs and lots of it... showing up
is Offline   Reply With Quote
Old 05-24-16, 11:01 AM
  #40
 
Superior Newbie
Join Date: May 2016
Likes: 0
so maybe it is kidneys does it have to be painful or can it go unnoticed?
is Offline   Reply With Quote
Old 05-24-16, 11:22 AM
  #41
 
Mr I's Avatar
 
Founding Member
Join Date: Nov 2004
Location: Self Righteous Brit
Likes: 1241
We aren't doctors bro

See a doc
is Online   Reply With Quote
Old 05-24-16, 11:32 AM
  #42
 
epix00's Avatar
 
Founding Member
Join Date: Jul 2004
Likes: 200
im guessing parasite.
is Online   Reply With Quote
Old 05-24-16, 12:55 PM
  #43
 
Bouncer's Avatar
 
Administrator
Join Date: Jul 2003
Location: California
Likes: 5398
Kidney issues can sneak up on you for sure. Doctor appointment now bro. We cant diagnose.
chuckz28 likes this.
is Online   Reply With Quote
Old 05-24-16, 03:26 PM
  #44
 
Bouncer's Avatar
 
Administrator
Join Date: Jul 2003
Location: California
Likes: 5398
or you could megadose. 150mgs dbol day and 3 grams test a week. if no response you arent alive any longer. lol
is Online   Reply With Quote
Old 05-24-16, 07:07 PM
  #45
 
Mr I's Avatar
 
Founding Member
Join Date: Nov 2004
Location: Self Righteous Brit
Likes: 1241
Going back to receptors I think it's a term that gets thrown around. We know for example that over time you're body would become less responsive to opiates so that you would need to take more to get the same result.

What would you term this? Becoming less receptive ?, but when people start talking about clearing receptor sites etc it just sounds bro science bunk

Sex hormones taken exogeneousely like testosterone keep working forever in general it's only the ageing process that gets in the way of its efficacy IMO
is Online   Reply With Quote
Old 05-24-16, 07:16 PM
  #46
 
Bouncer's Avatar
 
Administrator
Join Date: Jul 2003
Location: California
Likes: 5398
Quote:
Originally Posted by Mr I View Post
Going back to receptors I think it's a term that gets thrown around. We know for example that over time you're body would become less responsive to opiates so that you would need to take more to get the same result.

What would you term this? Becoming less receptive ?, but when people start talking about clearing receptor sites etc it just sounds bro science bunk

Sex hormones taken exogeneousely like testosterone keep working forever in general it's only the ageing process that gets in the way of its efficacy IMO
i think it really just boils down to this..

The same dose that got you from 180lbs to 205lbs is not gonna be the same dose you need to get up to 230lbs etc..

This guy sounds like he abused stuff early on and got great results but the body grew on that and now needs even more to get results.

Problem he faces is that extreme doses = serious risk to health. There is only so much the body can take before you pay the price.
is Online   Reply With Quote
Old 05-24-16, 08:01 PM
  #47
 
StanG's Avatar
 
Superior Amateur
Join Date: Aug 2012
Likes: 122
Just because there is no truth to receptor saturation or down-regulation does not mean that there are not other rate limiting factors when it comes to muscle development and growth, there definitely are.
One of them which is fairly well know is myostatin. Another can be as simple as your genetic make up. There are genetic limits that we work very hard to surpass and while I engaged in a debate with someone earlier on the topic or receptor saturation they did bring up the excellent point of the body striving to be in homeostasis. Part of this IMO is the body striving to meet the gentic make u it has been assigned at birth. What does this mean? This means the more you surpass these genetic limits the harder the body works to bring you back withing the pre ordained genetic limits that are compriced within your gentic make up.
As bouner said it is obvious that it is or becomes much harder to build muscle once you are at say 250 than it was getting from 200-225 and so on.
I am a firm believer that while recetor saturation or down-regulation is a myth that you still need to take breaks from using aas, not just kee increasing your doses etc. This is why quitee often advanced bodybuilder utilize techniques such as short burst cycles etc to blast through plateaus. You can go off for 8 weeks, do a carb cyce or low caarb ddiet as a form of a nutritional prime and then do a short, high dose burst cycle at a very high caloric intake to force the body to grow. You caan also change u your training to HIT trINING ETC.
tHERE ARE SEVERAL METHODS YOU CAN USE BUT TIME OFF IS, imo, STILL VERY IMPORTANT.
Bouncer likes this.
is Online   Reply With Quote
Old 05-25-16, 03:49 AM
  #48
 
Superior Newbie
Join Date: May 2016
Likes: 0
what do you mean by parasite? epixoo
is Offline   Reply With Quote
Old 05-25-16, 03:58 AM
Smile
  #49
 
Mr I's Avatar
 
Founding Member
Join Date: Nov 2004
Location: Self Righteous Brit
Likes: 1241
Quote:
Originally Posted by thedon768 View Post
what do you mean by parasite? epixoo
Thedon, don't listen too much to us. Don't worry, just go to the docs and tell them it's unexplained weight loss and take it from there.
is Online   Reply With Quote
Old 05-25-16, 05:26 AM
  #50
 
Superior Newbie
Join Date: May 2016
Likes: 0
ok mr i thank you
is Offline   Reply With Quote

SEO by vBSEO 3.6.0