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  #1  
Old 02-04-07, 10:24 AM
 
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Proviron. Why is this not talked about more?

Seems to me like Proviron should be used during any testosterone based cycle for various reasons. Here are a few cut and pasted paragraphs about provirion. I put a few real points of interest in bold for those who wont take the time to read.


Proviron has four distinct uses in the world of bodybuilding. The first being the result of its structure. It is 5-alpha reduced and not capable of forming estrogen, yet it nonetheless has a much higher affinity for the aromatase enzyme (which converts testosterone to estrogen) than testosterone does. That means in administering it with testosterone or another aromatizable compound, it prevents estrogen build-up because it binds to the aromatase enzyme very strongly, thereby preventing these steroids from interacting with it and forming estrogen. So Mesterolone use has the extreme benefit of reducing estrogenic side-effects and water retention noted with other steroids, and as such still help to provide mostly lean gains. Its also been suggested that it may actually downgrade the actual estrogen receptor making it doubly effective at reducing circulating estrogen levels.

The second use is in enhancing the potency of testosterone. Testosterone in the body at normal physiological levels is mostly inactive. As much as 97 or 98 percent of testosterone in that amount is bound to sex hormone binding globulin (SHBG) and albumin, two proteins. In such a form testosterone is mostly inactive. But as with the aromatase enzyme, DHT has a higher affinity for these proteins than testosterone does, so when administered simultaneously the mesterolone will attach to the SHBG and albumin, leaving larger amounts of free testosterone to mediate anabolic activities such as protein synthesis. Another way in which it helps to increase gains. Its also another part of the equation that makes it ineffective on its own, as binding to these proteins too, would render it a non-issue at the androgen receptor.

Thirdly, mesterolone is added in pre-contest phases to increase a distinct hardness and muscle density. Probably due to its reduction in circulating estrogen, perhaps due to the downregulating of the estrogen receptor in muscle tissue, it decreases the total water build-up of the body giving its user a much leaner look, and a visual effect of possessing "harder" muscles with more cuts and striations. Proviron is often used as a last-minute secret by a lot of bodybuilders and both actors and models have used it time and again to deliver top shape day in day out, when needed. Like the other methylated DHT compound, drostanolone, mesterolone is particularly potent in achieving this feat.

Lastly Proviron is used during a cycle of certain hormones such as nandrolone, with a distinct lack of androgenic nature, or perhaps 5-alpha reduced hormones that don't have the same affinities as DHT does. Such compounds, thinking of trenbolone, nandrolone and such in particular, have been known to decrease libido. Limiting the athlete to perform sexually being the logical result. DHT plays a key role in this process and is therefore administered in conjunction with such steroids to ease or relieve this annoying side-effect. Proviron is also commonly prescribed by doctors to people with low levels of testosterone, or patients with chronic impotence. Its not perceived as a powerful anabolic, but it gets the job done equally well if not better than other anabolic steroids making it a favorite in medical practices due to its lower chance of abuse.

Mesterolone is generally well liked nonetheless as it delivers very few side-effects in men. In high doses it can cause some virilization symptoms in women. But because of the high level of deactivation and pre-destination in the system (albumin, SHBG, 3bHSD, aromatase) quite a lot of it, if not all simply never reaches the androgen receptor where it would cause anabolic effects, but also side-effects. So its relatively safe. Doses between 25 and 250 mg per day are used with no adverse effects. 50 mg per day is usually sufficient to be effective in each of the four cases we mentioned up above, so going higher really isn't necessary. Unlike what some suggest or believe, its not advised that Proviron be used when not used in conjunction with another steroid, as it too is quite suppressive of natural testosterone, leading to all sorts of future complications upon discontinuation. Ranging from loss of libido or erectile dysfunction all the way up to infertility. One would not be aware of such dangers because Proviron fulfills most of the functions of normal levels of testosterone.

Letīs delve into some of the positive points of this drug before we go any farther. Androgen Receptors are found in fat cells as well as muscle cells(5), and whilethey act on the AR in muscle cells to promote growth, they also act directly on the AR in fat cells to affect fat burning.(9)(3) The stronger the androgen binds to the A.R, the higher the lipolytic (fat burning) effect on adipose (fat)tissue(6)(2). As if thatīs not enough good news, some steroids (notably, testosterone) even increase the numbers of A.R. in muscle and fat (9)(7). Thus, if you are taking a simple stack of proviron and testosterone, youīll have more of the test you shoot as free testosterone floating around building muscle (compliments of the Proviron), more androgen receptors to be bound to (compliments of your testosterone) by your Proviron, thus causing more fat loss. Testosterone and Proviron are a very nice synergistic stack, pretty nearly an "ideal" stack of an oral and injectable, because both drugs will actually act to enhance the effect of the other.

So what we have here is a steroid which can basically make other steroids more effective by preventing their conversion into estrogen, as well as increasing the amount of circulating free testosterone in your body. This of course all provides a more hardened and quality look to muscles. Proviron is very much a "synergistic" drug in this respect, and itīs inclusion in any cycle would definitely make all of the other steroids perform better, and provide better gains. This is all compounded by the fact that proviron is a very lipolytic (fat-burning) drug.
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  #2  
Old 02-04-07, 10:27 AM
 
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Plus Proviron is not a 17-aa drug and thus puts a considerably less amount of strain on the liver.
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  #3  
Old 02-04-07, 12:30 PM
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yep already knew all that i use proviron in all my cycles. my guess is people dont use it cuzz of the cost. real human grade is pricy.
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  #4  
Old 02-04-07, 12:50 PM
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price is the biggest thing...and availablity....but its the best drug, i love it...drink some graperfruit juice with it and absorb even more
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  #5  
Old 02-04-07, 01:22 PM
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Originally Posted by Stonecold54
price is the biggest thing...and availablity....but its the best drug, i love it...drink some graperfruit juice with it and absorb even more
yup -
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  #6  
Old 02-04-07, 08:41 PM
 
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how much grape fruit juice. anyone have any literature about grapefruit and proviron?
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  #7  
Old 02-05-07, 12:07 AM
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What's the word on proviron and hairloss? I've heard conflicting views. I'd like to try it with my next cycle if the chances of hairloss are low.
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  #8  
Old 02-05-07, 12:10 AM
 
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Originally Posted by hitmansb
What's the word on proviron and hairloss? I've heard conflicting views. I'd like to try it with my next cycle if the chances of hairloss are low.
Well I know its essentially DHT, DHT has been linked to such side effects.
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  #9  
Old 02-05-07, 12:18 AM
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Well I know its essentially DHT, DHT has been linked to such side effects.
I can't risk it then. Winny caused me to shed a lot...it took a year and a half of extra strength Rogaine to reverse the damage (I was lucky)....so no DHT-like drugs for me anymore.
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  #10  
Old 02-05-07, 12:21 AM
 
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Originally Posted by hitmansb
I can't risk it then. Winny caused me to shed a lot...it took a year and a half of extra strength Rogaine to reverse the damage (I was lucky)....so no DHT-like drugs for me anymore.
Ya but the same can be said for test. Increased androgen levels has been linked to hair loss also. Pretty much anything has been linked to hair loss.
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  #11  
Old 02-05-07, 12:24 AM
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Ya but the same can be said for test. Increased androgen levels has been linked to hair loss also. Pretty much anything has been linked to hair loss.
I take propecia...so I don't worry about taking moderate doses of test...as the finasteride prevents conversion to DHT.
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  #12  
Old 02-05-07, 09:22 AM
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One of the ingredients in my best cycle. Test prop, tren a, proviron. Awesome stuff. No need for nolva either.
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  #13  
Old 02-05-07, 01:58 PM
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Ya but the same can be said for test. Increased androgen levels has been linked to hair loss also. Pretty much anything has been linked to hair loss.
i never had a problem with hair loss on proviron. 50mgs per day.
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  #14  
Old 02-06-07, 06:37 AM
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people don't use it as much because of all the new anti e's around
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  #15  
Old 02-06-07, 09:42 AM
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i've def heard good stuff about it =)
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  #16  
Old 02-06-07, 09:59 AM
 
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people don't use it as much because of all the new anti e's around
ya but it does alot more then anti-e's..
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  #17  
Old 02-06-07, 10:35 AM
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ya but it does alot more then anti-e's..
when you consider the adverse cholesterol effects of anti-e's like a-dex its worth sticking to Pro v and Nolva, and like you say Pro V is supposed to bring out the best of other aas
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  #18  
Old 02-10-07, 07:32 AM
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I use Masteron, which is the same thing as Proviron but better
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  #19  
Old 02-10-07, 10:11 AM
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I use Masteron, which is the same thing as Proviron but better
ummmm....well....no
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  #20  
Old 02-10-07, 10:52 AM
 
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Quote:
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I use Masteron, which is the same thing as Proviron but better
explain why and how it is better. don't just post opinions as fact please.
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  #21  
Old 02-11-07, 12:15 AM
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ummmm....yeah.

So you have never heard of Masteron??
Obviously you havent or you wouldnt be asking.....

And it isnt an opinion its a fact.

You know whats funny......
I can make a state but I have to back it up. But when stone does the same thing......nothing??

Anyways........

Masteron chemical structure is 2 alpha-methyl-17 beta-hydroxy-5 alpha-androstan-3-one.

Proviron chemical structure is 1 alpha-methyl-17 beta-hydroxy-5 alpha-androstan-3-one.

Proviron is the oral form of Masteron, thus Masteron is an injectable.

Thus it is better as we all know......injectables are better then orals.
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  #22  
Old 02-11-07, 12:38 AM
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sorry stoney and bouncer he is right to a certain extent!
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