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#1
08-24-07, 01:49 PM
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EXEMESTANE
I have been away for a while and I've been reading about the anti E exemestane. Now it says that emestane is an irreversible, steroidal aromatase inactivator. What do they mean by irreversible? Does this mean it will permanently bind to the aromatase enzyme or forever stop the conversion of estrogens. If this is so wouldn't it be unhealthy? Snice you want all your hormones/enzymes to return to their natural state/balance after a cycle?
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#2
09-25-07, 02:28 PM
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It is irreversible to the molecule it attaches to. It irreversibly binds to the enzymes responsible for converting testosterone to estrogen. However, the body is in a constant state of turnover, which means that soon enough these inactive enzymes will be discarded and new ones will be made. If it were completely irreversible, there would be no need for repeated dosing.
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#3
09-25-07, 04:10 PM
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Quote:
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#4
09-28-07, 10:42 PM
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good info taylor26
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