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2018 Study - Deca Dick Explained

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  • Bouncer
    replied
    Originally posted by chuckz28 View Post
    https://www.ncbi.nlm.nih.gov/m/pubmed/8770664/

    Nitric oxide mediated erectile activity is a testosterone dependent event

    Based on presented data we conclude that testosterone or a metabolite plays a direct role in erection acting through an effect on nitric oxide synthase within the corpora cavernosa.

    Tapatalk sucks balls
    ahh that's interesting.

    i can say this with 100% certainty. tests ability to raise NO is much stronger then deca's reduction of NO. my girl is sore all the time because of my NO levels. :D

    Leave a comment:


  • chuckz28
    replied
    Originally posted by Bouncer View Post
    I'm not so sure. As long as I run test at equal dose of deca im good. What's test got to do with NO2

    Sent from my Moto G6 using Tapatalk
    https://www.ncbi.nlm.nih.gov/m/pubmed/8770664/

    Nitric oxide mediated erectile activity is a testosterone dependent event

    Based on presented data we conclude that testosterone or a metabolite plays a direct role in erection acting through an effect on nitric oxide synthase within the corpora cavernosa.

    Tapatalk sucks balls

    Leave a comment:


  • Bouncer
    replied
    Originally posted by chuckz28 View Post
    Good info. So it has nothing to do with prolactin as some have suggested via blood work. Sounds like simply taking Cialis and maybe even a small dose of masteron while on deca should alleviate deca dick.
    I'm not so sure. As long as I run test at equal dose of deca im good. What's test got to do with NO2

    Sent from my Moto G6 using Tapatalk

    Leave a comment:


  • chuckz28
    replied
    I don't even use gear bro but there are people who will regardless of the negatives. This just gives some ideas to try for guys that will do it regardless.
    Originally posted by redback View Post
    Lol so the other issues mentioned dont concern you?
    Tapatalk sucks balls

    Leave a comment:


  • redback
    replied
    Originally posted by chuckz28 View Post
    Good info. So it has nothing to do with prolactin as some have suggested via blood work. Sounds like simply taking Cialis and maybe even a small dose of masteron while on deca should alleviate deca dick.
    Lol so the other issues mentioned dont concern you?

    Leave a comment:


  • chuckz28
    replied
    Good info. So it has nothing to do with prolactin as some have suggested via blood work. Sounds like simply taking Cialis and maybe even a small dose of masteron while on deca should alleviate deca dick.

    Leave a comment:


  • redback
    replied
    I had never even tried nandrolone until recently but I knew it had to be bad news from the sides I was getting. Test is best.

    Leave a comment:


  • Bouncer
    started a topic 2018 Study - Deca Dick Explained

    2018 Study - Deca Dick Explained

    Now we know why nandrolone, an anabolic steroid (also known as 19-nortestosterone used in the form of esters such as nandrolone decanoate/Deca-Durabolin) causes erectile dysfunction and is often referred to as “Deca Dick.” This synthetic anabolic steroid has been available for decades. Early potential uses were for osteoporosis, anemia and muscle wasting. Anecdotal reports by bodybuilders suggest that nandrolone decreases joint pain from lifting heavy weights. Nandrolone binds to androgen receptors with greater binding affinity than testosterone, contributing to enhanced muscle growth. Nandrolone esters are among the most widely used steroids worldwide for medical use and to improve physique and performance.



    A new study in the Journal Steroids, March 2018, found that nandrolone combined with strenuous resistance training reduces vascular nitric oxide bioavailability and impairs endothelium-dependent vasodilation. Nandrolone can inhibit erectile function and cause sexual impairment as well as increase blood pressure and cardiovascular disease. Nandrolone plus strenuous resistance training increased reactive oxygen species (ROS, free radicals) that damage cellular tissues. It also drastically reduced vascular nitric oxide bioavailability. Nandrolone also increased arterial wall thickening and endothelial dysfunction. Nandrolone may increase the risk of cardiovascular disease and erectile dysfunction by decreasing dihydrotestosterone (DHT!), which is the active androgen involved in nitric oxide-meditated penile erections. Transdermal DHT is aging men has been shown to increase early morning erections and ability to maintain them.



    5-alpha-reductase enzyme normally converts testosterone in the prostate gland and hair follicle to DHT. DHT can cause prostate enlargement and alopecia (hair loss). Treatment of benign prostatic hypertrophy and alopecia with the drug finasteride lowers DHT but has side effects such as erectile and endothelial dysfunction. I am very concerned that finasteride taken for hair loss and benign prostatic hypertrophy may cause erectile and endothelial dysfunction and increase the risk of cardiovascular disease!



    Many anabolic steroid users use nandrolone because it does not convert into DHT. DHT can enhance hair loss (alopecia). This is one of the reasons why men use nandrolone, or Deca, as a replacement for testosterone because it could alleviate the development of androgenic alopecia. Because nandrolone does not raise DHT, it has less effect on hair loss than exogenous testosterone (with its subsequent conversion to DHT). That’s why nandrolone may be beneficial in hypogonadal men concerned with alopecia. The downside is that while nandrolone might prevent alopecia hair loss, it may have detrimental effects on endothelial vascular and erectile function and increased potential risk of cardiovascular disease.



    Nandrolone use lowers levels of luteinizing hormone and testosterone through negative feedback therefore, lowering DHT formation, but DHT is required for proper nitric oxide function. By inhibiting DHT, you lower nitric oxide bioavailability and endothelial function. It is theorized that nandrolone should be administered with testosterone (“stacked”) to provide DHT and prevent erectile dysfunction. However, specific in-vivo studies examining the effects of testosterone with nandrolone in humans have not been published. Very little scientific research exists regarding the use of nandrolone and, as such— further human studies are needed.
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