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Old 07-19-16, 01:48 PM
HGH benefits
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HGH benefits
Source - HGH benefits | WorldHGH

Although HGH is popular, too few complex and grounded information about the HGH benefits exist.
Growth hormone, as other hormones, influences whole body and regulate many systems – muscular, skeletal, epithelial, cardiovascular, sexual and even nervous.
Further article describes benefits of growth hormone and will help you to understand if they fit your purposes.
HGH benefits for muscle growth


1) Increases muscle mass

Growth hormone via IGF-1 and independently has strong anabolic effects. Major muscle gains is caused by binding to IGFR1 – IGF receptor – that induce protein synthesis. It leads to accelerated growth of muscles – main of growth hormone benefits.



Another anabolic mechanism of HGH – increasing the amount of muscle cell nucleus.
Quantity of nucleus is limitation factor of muscle growth, and HGH induces satellite cell proliferation and fusion with muscle cell. The fusion enlarges the cell and gives it an extra nucleus.

2) Induces division of muscle cells

It is still unclear whether skeletal muscle cells can divide or not, but many athletes claim that it is possible when you use growth hormone.

This benefit of growth hormone is great, because it allows you to obtain more cells and then enlarge them by hypertrophy.
Cell dividing potency of HGH can explain the tremendous rise in bodybuilders muscle mass, that was observed in 90-s, when growth hormone became available and commonly used. Current participants of Mr. Olimpia are 30-40 lbs larger than athletes of 70-80-s.



3) Anticatabolic activity.

GH administration shows decreased breakdown of aminoacids and their better disposal and use for muscle growth, thus improving nitrogen balance and anabolism. Experiment shows, that GH reduced leucine oxidation during endurance exercises by 50% and reduce nitrogen (protein excretion) in the urine [14]
Growth hormone also blocks cortisone to cortisol converse. Cortisol is the main catabolic hormone, which is responsible for muscle diminishing. So, its reducing is one of the HGH benefits.

FAT BURNING BENEFITS OF HGH
Ability of HGH to decrease fat mass – is one of the greatest HGH benefits.



How does HGH burns fat?

In 3 ways:

1) Increasing level of free fatty acids (FFA), thus enhancing their oxidation and using as a energy source.
Conversing thyroid hormone T4 to more active T3 form, that accelerates metabolism.
2) Accelerating RMR (resting metabolic rate)

Another benefit of growth hormone – you don’t need to keep strict diet to decrease body fat, because growth hormone uses fat as energy.
Research performed by New England Journal of Medicine showed 14 % decrease in fat body mass after 6 months of HGH treatment in low dose [15]. Patients didn’t change diet neither performed any exercises. Major results were fixed within first three months of using. Results that show sportsmen that train in the gym and keep high-protein diet are significantly better.

HGH effects on bones and ligaments

1) Increases bone density
Bone density is a measured by amount of minerals per square centimeter of bones. When the density is low, bones are fragile and easier to break. Extremely low density of bones is called “osteoporosis», however, reduced density is much more common problem and is caused by decreased collagen and osteocalcin levels. Study of Antoniazzi [3] showed that growth hormone directly increase both of these factors, thus improving bone density.
This fact provides several important growth hormone benefits for sportsmen, because high-density bones are stronger than low-density and secured from bone traumas.

2) Heals joints and ligaments
Many athletes have problems with pain in joints in ligaments. Pain can appear on the training or in the resting time and indicate that joints and ligaments are damaged and need healing.
Increased collagen synthesis is also useful for joints and ligaments healing. Collagen is main body protein constitute about 30% of all body proteins. Collagen is mostly contained in joints, ligaments and bones and is responsible for their reparation. People who use HGH, notice that joints reapirs rapidly since the first days of using. This effect is coincide with another growth hormone benefit – increasing strength, that is connected with growth hormone healing potency.

HGH benefits for immune system



Many cells, which regulate our immune system, such as T-cell, NK- cells and B-cells have IGF-1 receptors and are stimulated by Growth hormone. Activation of the immune cells help body to resist illnesses and heal already existing diseases.

1) T-CELLS.

Scientists found that main immune organ – thymus – that product T-cells atrophies in people, who have growth hormone deficiency [5]. The same process of thymus atrophy is observed during aging and coincides with decreasing level of Growth hormone. Later studies precisely prove relation between level of growth hormone and thymus function. GH was shown to revive thymus and enhance its function to produce immune T-cells.

2) NK-cells (natural killer cells)


Natural killer cells that complement T-cells are also can be stimulated by HGH. This function is still active even after GH treatment.

3) B-cells. Growth hormone is able to augment immunoglobulin, thus stimulating B-cells to resist illnesses by secreting antibodies.


4) Lengthens life of cell

HGH benefits make it popular in anti-aging therapy, because it prevents cell aging and death. Telomeres that indicate age of the cell are situated on the ends of chromosome. After each cell division, telomere shortens and when it becomes too short, cell loses ability to divide, ages and dies.
Growth hormone protects cell from fraying, so cell doesn’t need to divide often and the organism ages slower.

Other HGH benefits


1) Improves cholesterol level

Study of Johan Verhelst and Roger Abs [16] about HGH influence on cholesterol level showed that growth hormone decreases total cholesterol level by 7% and turns it to normal healthy state.
The amount of “bad» low-density lipoprotein (LDL) decreased . This effect was caused by improvement of LDL recetor function in the liver and lead to the higher LDL intake as a body fuel.
And «good” cholesterol HDL (HIGH-DENSITY LIPORROTEIN) remained at the same level.

2) Betters sleep

Improvement of sleep – one of the first perceptible HGH benefits, that appears since the first days of using growth hormone. Users report that recovery of muscular and nervous system is better.
High level of HGH increases cyclic alternating pattern rate – CAP rate (percentage of NREM “deep» sleep). Main metabolic processes of recovery take place in the deep sleep phase, so its enlargement affects well both sport results and good mood.

3) Betters skin

Human growth hormone benefits caused by increased collagen and elastin synthesis affect skin condition, making it more elastic and clean. The skin is constructed of collagen and elastin fibers and these fibers need regular repair to keep skin healthy.
Growth hormone is able to remove and smooth age wrinkles. The wrinkles appear when collagen and elastin synthesis decrease and skin dehydrate. Both of these factors are partly caused by deficiency of HGH an, thus, can be reduced by using growth hormone.

4) Enhances libido

Althought, many HGH users report that they have better libido and sexual capacities mechanism of this effect is not clearly understood. It can be caused by mediated influence on hypothalamus-pituitary-testicles axis. It seems to be, that sexual improvement is caused by other HGH benefits influence on the whole body.


5) Improves cardiovascular function

Many studies on humans and rats showed that Growth hormone deficient people have significantly increased risk of heart failure and other cardiovascular diseases [8]. GHD patients have adverse lipid profile, high level of BAD low-density cholesterol, risk of hypertension, increased coronary risk. Growth hormone administration experiment on rats performed byRenhui Yang [9] showed that growth hormone helps to prevent heart diseases and fight with already existing. treatment with growth hormone increased cardiac index (shows heart ability to pump blood well), stroke volume index (heart capacity to excrete blood), and left ventricular maximum (show strength of the heart).

6) Betters vision

Although improvement of vision, exactly night vision is noted by elderly users of HGH, younger users can feel vision benefits of HGH too.

Growth hormone improves tonus of muscles that hold the lens;
Prevents retina cells from degeneration;
Prevents cataract and glaucoma.
Better memory and cognitive function

Several studies DEMONSTRATED THAT COGNITIVE functions are related to GROWTH HORMONE level and HGH decrease that is common for people older than 30 years. Michael Vitiello and Baker LD [13] conducted experiments to evaluate how increasing level of HGH improves cognitive functions, particularly executive function, IQ and memory.
Results after 10 weeks of treatment showed significant rise in executive function (ability to concentrate, think rapidly, remember information connected with usual life), ability to memorize and solve intellectual tasks (IQ rise).
It is not clear whether growth hormone influence brain efficiency directly or via influence of other HGH benefits.


7) Improves mood

Among all HGH benefits, good mood is the most pleasant. Mood disturbance are often caused by troubles with endocrine system, particulary by the lack of thyroid hormones, lack or excess of estrogen or testosterone and low level of growth hormone.
Highly interesting surveys were made by two endocrinologists – Dr. Thierry Hertoghe and Edmund Chain, which gives data about HGH benefits in psychological improvement of users. People, who were using HGH answered questions about their well-being

Psychological benefits of growth hormone

IMPROVED ENERGY LEVEL – 84 %
Attitude toward life – 78 %
Improved emotional state (71.4%)
* Improved resistance to stress ((83.7%)
* Significantly decreased Anxiety (calmer) (73.5%)
* Improved sense of power (77.8%)
* Depression improved or eliminated (82.7%)



References

1) D J O’Halloran, A Tsatsoulis, R W Whitehouse – Increased bone density after recombinant human growth hormone (GH) therapy in adults with isolated GH deficiency
2) Agnieszka M. Lichanska, Michael J. Waters – How growth hormone controls growth, obesity and sexual dimorphism
3) Franco Antoniazzi, MD Francesco Bertoldo, MD Monica Mottes, PhD – Growth hormone treatment in osteogenesis imperfecta with quantitative defect of type I collagen synthesis
4) Banks WA1, Morley JE, Farr SA – Effects of a growth hormone-releasing hormone antagonist on telomerase activity, oxidative stress, longevity, and aging in mice.
5) Growth Hormone to Increase Immune Function in People With HIV
6) Verrillo E1, Bizzarri C, Bruni O – Effects of replacement therapy on sleep architecture in children with growth hormone deficiency.
7) CP Velloso – Regulation of muscle mass by growth hormone and IGF-I
8) Philipp Dreifuss, MD – Cardiac Effects of Growth Hormone
9) Renhui Yang, MD; Stuart Bunting, PhD; Nancy Gillett, – Growth Hormone Improves Cardiac Performance in Experimental Heart Failure
10) Dr. Laura D. Baker, PhD, Ms. Suzanne M. Barsness – Effects of Growth Hormone–Releasing Hormone on Cognitive Function in Adults With Mild Cognitive Impairment and Healthy Older Adults
11) Fitzgerald, Susan – Can a Growth Hormone-Stimulating Drug Improve Cognitive Function?
12) Dr Ben Green MRCPsych FHEA – Human Growth Hormone In The Treatment Of Biological Depression
13) Michael V. Vitiello, PhD,* Robert S. Schwartz, MD, Karen E. Moe – Growth hormone releasing hormone improves the cognition of healthy older adults
14) Niels Møller and Jens Otto Lunde Jørgensen – Effects of Growth Hormone on Glucose, Lipid, and Protein Metabolism in Human Subjects
15) Dr. Daniel Rudman – HGH Injection Study in the New England Journal of Medicine
16) Johan Verhelst and Roger Abs – Cardiovascular risk factors in hypopituitary GH-deficient adults

Last edited by worldhgh; 07-19-16 at 01:59 PM.
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Old 07-20-16, 05:51 AM
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Very Useful Info. Thanks bro
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