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Old 08-18-16, 09:34 AM
TrapsBrah's Avatar
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Baicalin, along with its aglycone baicalein, is a positive allosteric modulator of the benzodiazepine site and/or a non-benzodiazepine site of the GABAA receptor.[2][3][4] In mice, baicalin produces anxiolytic effects without sedative or myorelaxant effects.[5][6] It is thought that baicalin, along with other flavonoids, may underlie the anxiolytic effects of S. baicalensis and S. lateriflora.[7][8]

Baicalin is a known prolyl endopeptidase inhibitor.[9] It induces apoptosis in pancreatic cancer cells.[10]
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