Does Nolva stop gains during a cycle?

[Shibby]

I see alot of people in different threads talking about whether or not Nolva inhibits gains during a cycle. So what do those who know about it think?

[teekahty]

Nolva prohibits bloat ... some people equate bloat with gains thus they come to the conclusion because they are not puffed out with water . they are losing gains ... I use Nolva or some sort of anti-e with every cycle for the duration of the cycle


**********HOWEVER**********
You do not want to go with too high a dose of anti-e depending on your goals because (posted elsewhere by Spidey) Estrogen does play a role in mass building. If you totally supressed estrogen production, it would limit your gains as well as be very unhealthy for you. Estrogens play important roles in lipid metabolism, bone density and skin tone not to mention the health of your brain. Various estrogens are important messengers in the brain. They help regulate a lot of other hormones like testosterone, HGH, and I am sure many others. Trying to eliminate all estrogen would be very unwise IMO.

[Flex]

By Author L.rea Nolvadex Decrease IGF-1 production 23.5%....steroids like D-bol increase it so if I would have problems whit gyno I would lower the dose


.... and for the teekahty Clomiphene (Clomid) and tamoxifen (Nolvadex) are more precisely referred to as "selective estrogen receptor modulators." This is because their mode of action is not so simple as merely blocking the estrogen receptor. Estrogen receptors require not only hormone but also activation of regions of the receptor called AF-1 and AF-2. AF-1, to be activated, requires phosphorylation, while AF-2 can be activated by any of a number of cofactors, such as IGF-1.

As it happens, clomiphene and tamoxifen are estrogen receptor antagonists (blockers) in cells that depend on activation of the AF-2 region, while in cells which activate AF-1, these compounds are estrogens.

In some cells these drugs activate one of the types of estrogen receptor (ERa ) but are antagonists of the other type (ERb ).

The result is that these compounds are antiestrogenic in breast tissue, fat tissue, and in the hypothalamus, which is what we want in bodybuilding, but are estrogenic in bone tissue and with respect to favorable effect on blood lipid profile, both of which are, again, desirable. They also appear to have some estrogenic effect on mood, though this may be in only parts of the brain (the matter is not studied.)

[joe bigboy]

the only gains that nolva is gonna decrease is estrogen iduced bloat which most try to avoid anyway

[leanandmean]

only if you like to get moon face and puffy nipples lol

[CreepingDeath]

I agree with teekahty, I didnt lose any gains when I used nolv mid cycle......all I lost was the gyno the gains continued

[Flex]

I did not mean that you would stop gaining but studys have shown (Muscular Developement July 2004) that the gains would be better whitout nolva

[Bouncer]

Originally posted by Flex
I did not mean that you would stop gaining but studys have shown (Muscular Developement July 2004) that the gains would be better whitout nolva

Do you mean simple weight gain? Because they are talking about total weight gain, ie water fat and muscle. Nolva will simply stop some of the water gain, not muscle.

[Flex]

I mean LBM not water or fat

[Tinfish]

I love running nolva througout my entire winny cycle. really makes me look defined.

[MAXOVERLOAD]

How about .25mg of L-dex and 10mg of L-nolva ED.

I am on a cycle of :

Weeks 1-4 Anadrol 75mg ED
Weeks 1-12 T-400 @2x per wk @300mgs Ea
Weeks 1-10 EQ 400mg @2x per wk @200mgs Ea

Do i need that much of the L-dex & L-nolva. I have onlt been using the L-dex &L-nolva for 1 week and already look harder then in the past.

This was recomended by people on another board.

I dont have a prob with Gyno yet but i always suffer from bloat.

[MAXOVERLOAD]

Originally posted by MAXOVERLOAD
How about .25mg of L-dex and 10mg of L-nolva ED.

I am on a cycle of :

Weeks 1-4 Anadrol 75mg ED
Weeks 1-12 T-400 @2x per wk @300mgs Ea
Weeks 1-10 EQ 400mg @2x per wk @200mgs Ea

Do i need that much of the L-dex & L-nolva. I have onlt been using the L-dex &L-nolva for 1 week and already look harder then in the past.

This was recomended by people on another board.

I dont have a prob with Gyno yet but i always suffer from bloat.

Anyone???
Anyone???

[Skyefire]

Originally posted by MAXOVERLOAD
Anyone???
Anyone???

that is an ideal combo. be sure that you need it first, diet has a lot to do with how much you bloat.

[spidey]

Since Nolva decreases IGF-1, I think it is likely to impact gains at least a little bit. As Flex noted, SERMS like nolva are not the same as aromatase inhibitors like liquidex. Liquidex can actually lower estrogen levels to the point of being unhealthy if over used. Nolva can't lower estrogen levels at all. Rather, it selectively blocks estrogen from binding to the receptors in breast, fat and hypothalmic tissue while acting as an estrogen agonist in other tissues.

[spidey]

Originally posted by teekahty

**********HOWEVER**********
You do not want to go with too high a dose of anti-e depending on your goals because (posted elsewhere by Spidey) Estrogen does play a role in mass building. If you totally supressed estrogen production, it would limit your gains as well as be very unhealthy for you. Estrogens play important roles in lipid metabolism, bone density and skin tone not to mention the health of your brain. Various estrogens are important messengers in the brain. They help regulate a lot of other hormones like testosterone, HGH, and I am sure many others. Trying to eliminate all estrogen would be very unwise IMO.

WHOA...Did the great Teekahty just quote me?? Not worthy, not worthy (backs away bowing). :rofl: