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Got some Pregnyll...now I just need help with the dose.

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  • Got some Pregnyll...now I just need help with the dose.

    Guys and Gals,

    I have a box of HCG ( Pregnyll) and it contains 3 amps of 5000Iu and the 3 amps of solvent.

    I am running a sust only sycle that will be 2 weeks - 250mg a week, 4 weeks - 500mg week and last two weeks at 250mg a week. Total 8 weeks.

    This is my second cycle. 25 yrs, about 185 pounds and 15%BF.
    Been training for about 5 years naturally.

    I cannot get anything but Pregnyll, so although it is not ideal, It is all I have to use for PCT. I know I should start it around 3 weeks after last shot of sust, but I am unsure of how to split up the doses. Should I just have one shot of 5000IU a week for the three weeks or can you dissolve the HCG and preload in smaller doses. I am hoping that is advised as I think HCG should be injected a bit more regualy than once a week. Maybe 2500IU twice a week...i dunno.

    I know this probably sounds a bit confusing or maybe not the best option to the more experienced bro's out there, but it is either manipulate the HCG for post course or take nothiung and loose all my size.

    Any help and info on this would be great as I have not used HCG before and want to use as best I can

    Thanks in advance,

    Hit.

  • #2
    HCG is not optimum for PCT. It is suppressive in it's own right so your HPTA will not recover while you are using it.

    I would save it for a heavier cycle later. Your cycle is a pretty light one and just a little clomid or nolva should work nicely as PCT.

    On Heavy cycles where ball shrinking is an issue, you should run HCG during the last 2 weeks of the cycle at about 500 IU's ed. Then, after the proper waiting period, do your normal clomid/nolva for PCT. This gets your balls back up to size and gives the clomid/nolva something to work with.

    Comment


    • #3
      I agree with Spidey. For your light cycle, it really isn't necessary.

      Here's something I posted on another board about HCG:

      HCG is a glycoprotein that mimics luteinizing hormone (LH) in the body, stimulating the testes to produce testosterone even when natural LH isn't present (suppressed HPTA) or deficient. It's good for maintaining testicle size and function during a steroid cycle. Using HCG post-cycle though can be counterproductive, since the increased testosterone production is itself inhibitory to the hypothalamus and pituitary, delaying the actual recovery. Thus, if you're going to use HCG, it's preferable to use it during the cycle itself. A daily dose of 500 IU is typically sufficient, and in my opinion usage should not exceed 1000 IU per day (Doses over 1000 IU can cause or aggravate gynecomastia, and also have the potential to desensitize the leydig cells in the testicles to LH)

      I have used HCG during and post-cycle when required to ensure that the testicles are ready to go, and then begin clomid/nolvadex only after completing the HCG to restart my natural LH production.

      DrG
      Last edited by drgoodbody; 08-20-04, 01:34 PM.

      Comment


      • #4
        You can probably get away with not using it....UNLESS you have 'shrinkage'. If your nuts seem like they've shrunk at all, then you should use HCG...it'll make your recovery go a whole lot smoother. I'll post up the usage guide just in case someone who does need HCG happens to read this thread.

        Instructions: HCG (requires 2 needles, alcohol swabs)

        1. Swab top of sterile water vial with alcohol
        2. Draw up some sterile water
        3. Break off top of HCG ampule
        4. Use needle to squirt water into amp slowly (not too much, keep some water in syringe)
        5. Gently swirl water in amp until white powder dissolves
        6. Use second needle to draw solution out of ampule
        7. Swab top of sterile water vial with alcohol
        8. Inject HCG solution into sterile water vial (not too fast, gently)
        9. Repeat steps 4-8 with remaining water
        10. If any water remains in water syringe, inject into vial
        11. This leaves 5000iu HCG in 10mL of solution
        12. Take 1cc of HCG solution subcutaneously ever day for post-cycle therapy
        13. DO NOT SHAKE HCG!!! Invert vial gently before use to mix
        14. KEEP HCG REFRIGERATED

        Comment


        • #5
          Since I haven't posted it in awhile, here's the regimen I like to recommend for PCT:

          The following assumes 500iu/mL HCG, 20mg Nolvadex tabs, and 50mg Clomid tabs.

          Day 1: 1mL HCG, 1 tab Nolvadex
          Day 2: 1mL HCG, 1 tab Nolvadex
          Day 3: 1mL HCG, 1 tab Nolvadex
          Day 4: 1mL HCG, 1 tab Nolvadex
          Day 5: 1mL HCG, 1 tab Nolvadex
          Day 6: 1mL HCG, 1 tab Nolvadex
          Day 7: 1mL HCG, 1 tab Nolvadex
          Day 8: 1mL HCG, 1 tab Nolvadex
          Day 9: 1mL HCG, 1 tab Nolvadex
          Day 10: 1mL HCG, 1 tab Nolvadex
          Day 11: 1 tab Nolvadex, 2 tabs Clomid
          Day 12: 1 tab Nolvadex, 2 tabs Clomid
          Day 13: 1 tab Nolvadex, 2 tabs Clomid
          Day 14: 1 tab Nolvadex, 2 tabs Clomid
          Day 15: 1 tab Nolvadex, 2 tabs Clomid
          Day 16: 1 tab Nolvadex, 2 tabs Clomid
          Day 17: 1 tab Nolvadex, 2 tabs Clomid
          Day 18: 1 tab Nolvadex, 1 tab Clomid
          Day 19: 1 tab Nolvadex, 1 tab Clomid
          Day 20: 1 tab Nolvadex, 1 tab Clomid
          Day 21: 1 tab Nolvadex, 1 tab Clomid
          Day 22: 1 tab Nolvadex, 1 tab Clomid
          Day 23: 1 tab Nolvadex, 1 tab Clomid
          Day 24: 1 tab Nolvadex, 1 tab Clomid
          Day 25: 1 tab Nolvadex, 1/2 tab Clomid
          Day 26: 1 tab Nolvadex, 1/2 tab Clomid
          Day 27: 1 tab Nolvadex, 1/2 tab Clomid
          Day 28: 1 tab Nolvadex, 1/2 tab Clomid
          Day 29: 1 tab Nolvadex, 1/2 tab Clomid
          Day 30: 1 tab Nolvadex, 1/2 tab Clomid

          You'll get varying opinions on PCT, but this is what has always worked well for me.

          Comment


          • #6
            Is HCG supposed to be injected sub-Q? I'm glad I read this post.
            I would have went IM

            Comment


            • #7
              Can inject it either way, sub-q or IM. I believe there is some clinical evidence that IM provides a greater bioavailability tho.
              ----------------------

              Bioavailability of HCG after intramuscular or subcutaneous injection in obese and non-obese women.

              Chan CC, Ng EH, Chan MM, Tang OS, Lau EY, Yeung WS, Ho PC.

              Department of Obstetrics and Gynaecology, Queen Mary Hospital, The University of Hong Kong, SAR, China. [email protected]

              BACKGROUND: Obese women require higher gonadotrophin doses for ovarian stimulation and to trigger ovulation. The bioavailability of a drug is affected by its route of administration. Herein, the bioavailability of hCG was compared after intramuscular (i.m.) or subcutaneous (s.c.) injection in obese and non-obese women. METHODS: Twenty four Chinese women, 12 with a body mass index (BMI) 28 kg/m(2) and 12 with a BMI of 20-25 kg/m(2) were recruited as the obese and non-obese groups respectively. A single hCG injection was given intramuscularly on one occasion, and subcutaneously on a second occasion, separated by 4 weeks. Blood samples were taken at intervals for the pharmacokinetic study of hCG. RESULTS: Examination of the hCG plasma concentration-time curve showed the area under the curve (AUC) and maximum concentration (C(max)) of hCG to be significantly higher after i.m. injection than after s.c. injection in both the obese and non-obese groups. However, the AUC and C(max) values in obese women were significantly lower than in non-obese women, irrespective of whether i.m. or s.c. dosing was employed. CONCLUSIONS: Intramuscular dosing of hCG provided better bioavailability than s.c. dosing , but bioavailability was significantly less in obese women than in non-obese women

              Comment


              • #8
                Hitman, with the PCT you recommeded here...Are you saying that the first 10 days of HCG usage are when there is still active steroid in the body? So day 1 would basically start the day after your last shot of say enanthate? Or are yo recommending that PCT start when levels have already dropped? Sorry just confused about what you meant.

                Comment


                • #9
                  Can't you just use the amp of sterile water that comes with the Pregnyl kit? I was just gonna mix the 1ml of water with the powder, take 10 slin pins and preload 10 units of HCG in each which would be 500 iu, and stick them in the fridge. Is that exceptable?

                  Comment


                  • #10
                    I'd do one 5,000iu kit at 500iu a day for ten days in mid cycle and same at end.

                    Gets balls back fast!

                    Comment


                    • #11
                      Let me clarify: you'd wait (how long depending on clearance times of what you're running) until after your last shot cleared before starting the PCT. I'd wait until two weeks after my last shot of enanthate to start this particular PCT scheme.

                      Comment


                      • #12
                        I can't imagine he has any ball shrinkage from this light cycle. It's a waste of HCG IMO. Simple Clomid or Nolva therapy will do the trick just fine without turning him into a pin cushion.

                        Also, HCG INHIBITS THE HPTA. You will HINDER recovery by using HCG after your cycle. If you are bound and determined to use it, use it during the last two weeks of your cycle when HPTA inhibition doesn't matter since you're still taking test. Take 20mg ed nolva with it as HCG can cause gyno. Then, wait the appropriate waiting period and do a simple PCT with nolva or clomid.

                        Comment


                        • #13
                          I never read cycle length mine are usually quite long........

                          Comment


                          • #14
                            Originally posted by DangerousGround
                            I never read cycle length mine are usually quite long........
                            His cycle is only 8 weeks with rather light doses of test enan.

                            Comment


                            • #15
                              Originally posted by spidey
                              HCG is not optimum for PCT. It is suppressive in it's own right so your HPTA will not recover while you are using it.

                              I would save it for a heavier cycle later. Your cycle is a pretty light one and just a little clomid or nolva should work nicely as PCT.

                              On Heavy cycles where ball shrinking is an issue, you should run HCG during the last 2 weeks of the cycle at about 500 IU's ed. Then, after the proper waiting period, do your normal clomid/nolva for PCT. This gets your balls back up to size and gives the clomid/nolva something to work with.

                              What about a 500mg test cycle that is exceding 15 weeks. I havent noticed much ball shrinkage but I gotta be shut down. Should I use my hcg or nolva and clomid only?????thanx

                              Comment

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