Trying to uderstanding 17aa's a little...

[Deez Nuggets]

In regards to the affect on the liver.

Winstrol is a 17aa, so would would takign it orally be harder on the liver then injecting it? (dosaging being the same for both)?

[BENCH355ANIMAL]

Regardless of whether you take it orally or intramuscular.....it doesn't change it's 17-aa structure. It will still pass through the liver. If you have pills pop'em, if you have amps, then drink the liquid. There is no need to inject it if you can drink it and have the same effects.

[beefcake]

Injecting it will allow it to avoid a first pass through the liver, it'll still have to make a second pass but not as harsh as taking it orally. All of it will have to pass through the liver if taken orally.

[ROCKETW19]

Originally posted by beefcake
Injecting it will allow it to avoid a first pass through the liver, it'll still have to make a second pass but not as harsh as taking it orally. All of it will have to pass through the liver if taken orally.

:agree:

[DS-COUSIN]

Originally posted by beefcake
Injecting it will allow it to avoid a first pass through the liver, it'll still have to make a second pass but not as harsh as taking it orally. All of it will have to pass through the liver if taken orally.

:agree:

[shortz]

Originally posted by beefcake
Injecting it will allow it to avoid a first pass through the liver, it'll still have to make a second pass but not as harsh as taking it orally. All of it will have to pass through the liver if taken orally.

This is where the myth starts. You are only partially right. The drug goes through the liver numerous times whether you inject or ingest. It is not less toxic to the liver by injecting. The body uses very little of the drug when before it goes through the liver and kidneys.

Which brings me to my next point. Liver damage is over rated and kidney damage is under rated. The liver recovers rather quickly, where the kidneys may take a bit more of a beating over time.

[beefcake]

Originally posted by shortz
This is where the myth starts. You are only partially right. The drug goes through the liver numerous times whether you inject or ingest. It is not less toxic to the liver by injecting. The body uses very little of the drug when before it goes through the liver and kidneys.

Which brings me to my next point. Liver damage is over rated and kidney damage is under rated. The liver recovers rather quickly, where the kidneys may take a bit more of a beating over time.

If it avoids the first pass through, wouldn't that make it a little less hepatoxic than an oral? IE, wouldn't four passes through the liver be a little less toxic than five? I would think so. Why do you say that very little gets used until it goes through the liver and kidneys? Only prohormones need the liver for activation, not an active steroid. The main purpose of the kidneys and liver is for filteration not distribution. So why do you say a compound that is already in the blood stream isn't really being used?