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  • ??Arimidex??

    I'm thinking about starting on Arimidex, I hear the suggested dosage is 1mg ED. My buddies have shared their experiences of having dry mouth, shortness of breath and other side effects are there any other suggestion of using something else, maybe something better? Your advice would be very helpful.

  • #2
    I've never used a-dex, only letro. Letro is stronger and does great for keep the bloat down for me. Very possible that 1mg ed of a-dex is too much. Some people need different dosages than others. I used to use 1.25mg ed of letro and it was too much, now I only need .25mg ed and that does just fine.

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    • #3
      1mg a-dex eod usually... ed I never saw any difference, and like beefcake said letrozole is stronger and better imo, but we all react diff...

      K

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      • #4
        I would just go with letro, I hear that letro is more powerful than arimidex.

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        • #5
          these people are tellin you to use letro with out even knowing what you are on! thats not good. post your cycle and why you want l-dex or anything.

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          • #6
            Originally posted by moranitotongano
            I'm thinking about starting on Arimidex, I hear the suggested dosage is 1mg ED. My buddies have shared their experiences of having dry mouth, shortness of breath and other side effects are there any other suggestion of using something else, maybe something better? Your advice would be very helpful.
            First off rocket is right, post some more info. The starting does for ldex sould be .25mg a day and increase as needed. That could be some of your friends problems but those aren't the normal sides. Letrozole is stronger but caries more sides. in fact it really is too strong for most cycles.

            Note: SERM stands for selective estrogen-receptor modulators, a class of anti-estrogens that work by competing with the estrogen at the estrogen receptor sites. Aromatase inhibitors (AIs) are a class of anti-estrogens that work by preventing the aromatase enzyme from converting testosterone and its derivatives to estrogen and its derivatives.

            Nolvadex (Tamoxifen Citrate, Nolva) is SERM type anti-estrogen, the strongest of the fist generation. First off, if you only can afford or want one ancillary drug this is it. Nolvadex is not only one of the cheapest drugs ( an entire cycles worth can be had for less then 30 dollars) its the only drug proven to stop gynecomastia (gyno) and sometimes reverse it. It is also the single best defense against it. You should always have this drug on hand and at the least start using it if any symptoms of gynecomastia. However it is much better to run a small dose of Nolvadex throughout the cycle (10 to 20mg ed) to help reduce estrogen side affects and as a precautionary measure against gynecomastia. While it is rumored that Nolvadex will reduce your gains there no evidence that it does anything except reduce the amount of water that retain as a result of the excess estrogen caused primarily by the aromatase enzyme converting steroids to estrogens or there derivatives. This is one instance that an ounce of prevention is more then worth the pound of cure. The treatment dosage of Nolvadex for gynecomastia is around 60mg every day until symptoms subside.

            Sense Nolvadex is a highly selective SERM type anti-estrogen it mainly targets the mammary glands, which in English means that Nolvadex competes with the estrogen to bind the receptors in the breast (hence the selective part). This it will help prevent/treat gynecomastia while allowing other necessary estrogen activity.

            Nolvadex is also the preferred drug for post cycle therapy (PCT). Less sides and more effective then clomiphene citrate (clomid) It is commonly ran for 4 to 6 weeks after a cycle in a gradually reducing dosage. A simple PCT routine would be 40mg ed for two weeks then dropping the dosage down to 20mg every day for another 2 weeks.

            Note: the half-life of Tamoxifen Citrate is about 6 day, but it does not follow the typical half life curve, rather it has a secondary peak after a couple of days as well as some troughs, still if you are using a less then pleasant tasting research chemical you don’t need to take it every day, every other day will do just fine. Ever third day is a little to long though. Just make sure the total dosage you take any one-day is less then 40mg because if you go above that the side affects become increasingly prominent. Side affects include hot flashes, nausea, numbness and blurred vision.

            Clomiphene citrate (clomid) is another common (and cheap) SERM. However Clomid is not very effective as an anti-estrogen. Its primary use is for post cycle therapies. However due to the unwanted side affects of clomid and Nolvadex being more effective it is falling out of favor as PCT drug of choice. The sides are generally the same as Nolvadex with one glaring exception. Clomid acts like real estrogen in terms of affecting your emotions. In other words a 4-week PCT routine is like being menstrual for 4 weeks. The effective dosage for Clomid is 150 to 50mg ED. It has a half-life of around 5 days so every other day dosing is acceptable.

            Letrozole (letro)is the most powerful Aromatase inhibitor generally available. It is useful primarily when use very large amounts oh highly aromatizatable steroids, large amounts of mythel-test, Methandrostenolone, and very large amounts of testosterone, especially testosterone base. Please note that Nolvadex and Letrozole cancel each other out at a rate of 40% and you must increase the dosage accordingly if you wish to run them together. Letrozole is not recommended for most cycle primarily due to its strength and side affects. Running even a minimal amount of Letrozole can result in estrogen levels dropping far to low, causing hot flashes, dizziness, and a highly compromised lipid profile. It can also affect your sexual functions. Effective dosages start at about 1mg every day, up to 4mg every day (no one but a cancer victim should run it at this level.

            Anastrozole (Arimidex, ldex, Adex) is also a powerful aromatase inhibitor, but less so then letrozole. It is highly useful for reducing bloat caused by excess estrogen. Again it is too strong for most cycle however, anastrozole is effective in very small amounts so it can be used in moderation more easily then letorzole. Effective dosages start as low as .25mg every other day up to 1mg every day.

            Mesterolone (Proviron) is a mild aromatase inhibitor that has some added benefits. It is a dihydrotestosterone derivative that is a all purpose type drug that is primarily prescribed nowadays to treat impotence and as a fertility drug. Another use is to enhance the effect of testosterone as frees it up. This does not work as good in practice as it does theory but it does work well with other mentholated items. Also running it with highly suppressive compounds (Nandrolone Decanoate, Trenbolone.) will prevent/cure impotence (deca-dick, fina-dick). This drug is especially effective as a anti-estrogen when combined with a small amount of nolvadex. Some should always be kept on hand for emergency (of the gender relations kind). This is a dihydrotestosterone derivative so the same sides apply, high blood pressure and the like. Please note that overuse of Proviron could cause a bad case of sexual over stimulation and in some cases continuous penis erection. In reality this is not funny and can require surgery to relive the erection. The effective dosages of proviron start at 25mg and range as high as 250, with 50mg being the standard dosage for most things.
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            • #7
              Hey skyefire, do you have any studies or thoughts on aromasin?

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              • #8
                I am getting ready to try it now. Super chicken had a good post on it, let me see if I can find it.

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                • #9
                  from superchicken (sums it up for me, Like I said I am going to try it)

                  aromasin(exemestane)

                  --------------------------------------------------------------------------------

                  ORIGINALLY POSTED BY SUPERCHICKEN and stolen by tony touch from crankenstein

                  theres been a lot of talk on other boards about this lately, and a lot of bad information thrown out as well. i wanted to share the good info.

                  somone keeps posting how letrozole is the strongest and doesnt negatively affect cholesterol. this is not true. letrozole is NOT the strongest and it DOES negative affect cholesterol/lipid profile in a bad way.

                  aromasin(exemestane) is the best. this is why

                  both arimidex/ldex/anastrozole and femara/letrozole hurt your cholesterol. the way these 2 anti e's work is they inhibit the aromatase enzyme. by inhibiting the enzyme which converts testosterone to estrogen, you reduce or even come close to eliminating estrogen production. we need some estrogen to be healthy. the major drawback to this is without estrogen, your lipid profile gets ****ed.

                  exemestane works differently. it does not stop the body from producing estrogen. rather, it makes it so the estrogen is unable to bind to receptors by deactivating the binding enzyme. if the estrogen cannot bind, you simply will not get bloated or get gyno. the estrogen is crippled due to exemestane. however, since the estrogen is still floating around, it will not negatively affect your lipid/cholesterol profile.

                  anastrozole doesnt cause a rebound effect, and neither does exemestane, but letrozole does. this means after you stop the letrozole, your estrogen rebounds and goes pretty high for a while, eventually it normalizes. you can avoid this by tapering your letro dose down before stopping it, but that is a pain in the ass. higher than normal can mess many things up post cycle when you stop. since the hpta has a feedback loop is primarily controlled by estrogen, high estrogen will tell your hpta to produce less testosterone, because it thinks the high estrogen is caused by too much testosterone. this is fact. now post cycle, dont we want to raise our test levels, not lower them? of course! so rebounds are bad. if you use letro taper the dose off to zero over a couple weeks.

                  fyi- nolvadex(tamoxifen) is a SERM(Selective Estrogen Receptor Modulator). this means on certain tissue it can act antagonisticaly or agonistically. in the case of lipid profiles, it acts agonistically. so, running tamoxifen with your anti e's will IMPROVE your cholesterol profile even if not on cycle or using any gear or other anti e's. its just plain good for cholesterol.

                  one thing to keep in mind though when runing tamoxifen with letro. letro reduces blood levels of tamoxifen by over 50%. a study showed 2.5mg letro ed made nolva levels drop to 40% of what they were before adding letro. this does not mean you cant use tamoxifen with letro, it just means you need to use more, about double. 20mg of nolva will act like 8mg if running letro. so make sure you are aware of this because you will need to buy more nolva to compensate. this does not happen when mixing tamoxifen with anastrozole or exemestane, it only hppens with letro.

                  also, many people and myself experince a reduction of libido on letro. this doesnt happen w/ ldex or exmestane as far as i know, and in my own experience, and ive run all 3 quite a bit.

                  the best combo IS exemestane and tamoxifen together. your cholesterol will be as good as can be considering your on a cycle of steroids. the dose of aromasin will vary depending on the users needs and how much aromatizing gear is being taken. usually 10-25mg ed works well. run 10mg ed nolva to improve your cholesterol.

                  second best combo i feel is anastrozole(ldex) and tamoxifen. ldex dose ranges from usually .15mg ed to 1mg ed. run 10mg nolva ed to improve cholesterol.

                  thierd best is letro and nolvadex. letro doses usually range from 1-2.5mg ed. run 20mg ed nolva to improve cholesterol w/ letro.

                  you do not need to run nolva with any of these 3, i do recomend it though as it will improve cholesterol compared to using the anti e's alone without nolva.

                  so in order of strength, on a dose per dose basis(not mg per mg) aromasin is def the strognest, next is letro, and then ldex.

                  ive been running aromasin now for about 4 months, i wont switch back to ldex or letro. it works much better and its much healthier for cholesterol profiles.

                  i think we all need to stop only worrying about side effects that we can see visually. cholesterol KILLS many people around the world everyday(well not directly kills but leads to it). steroids are hrting us badly in this sense. steroids do mess our cholesterol up pretty badly, and we will pay for it later in life. now not many of us are going to stop using gear because of that, but we should at least take the proper other drugs to help minimize.

                  aromasin is only a little bit more expensive than ldex or letro, and its actually about the same price as many places sell ldex or letro for. but its more powerful and healthier. people spend money all the time on steroids which dont have as many side effects as some of the harsher, cheaper steroids. a few extra bucks for the proper anti e's is def money well spent.
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