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Yohimbine and Ephidrine

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  • Yohimbine and Ephidrine

    Having regard to the passage below I just wanted to ask "has anyone on here used the two together and how did they find it?


    "A possible synergism between yohimbine and ephedrine hasn't been thoroughly explored, and the information that exists is somewhat contradictory. In theory, they should work well together as yohimbine blocks one of the negative feedback mechanisms that would normally make ephedrine less effective. Cell culture studies confirm that yohimbine increases the lipolytic effects of beta(3) agonists (19). However, a study using rats indicated that yohimbine blocked the effects of the same beta(3) agonist, indicating that the two may antagonize each other (19). Additionally, a study on cardiovascular variables found that ephedrine and caffeine together were safe, but the addition of yohimbine may produce undesirable effects (20). So it is still unknown whether the combination of yohimbine and ephedrine produces any additional benefit, and whether it is justified by the potential dangers. "

    The above passage is taken from the link below
    http://www.uk-supplements.com/pg-art...les_id-69.html

  • #2
    I have never used both at the same time but I used Ephedrine HCL for the longest time. (Those energy pills at the gas stations) I'd take 2-4 of those badboys just everyday before work with my coffee back when I was doing lawn maintainance at a country club. That was back when I was 11% :(

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    • #3
      I don't like the 2 together. The combo makes my prostate hurt, interferes with urination, and I get uncomfortably nervous. I can use each separately without those symptoms. the synergy is bad, for me.

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      • #4
        I've taken the two. I drank a Redline (has yohimbine) and also took caffeine and ephedrine. I woulnd't recommend that. I should've had a heart attack. So that was the time I thought to myself that my tolerance has built up to high with fat burners and needed a break.

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        • #5
          I'm in my 4th week of the UD2. The first 3 weeks I used caffeine, synephrine, & green tea 3x/daily. This week I started using caffeine, ephedrine, & yohimbine 3x/daily. I definitely experienced more of a jittery, hyped up type of feeling, but nothing that is worrying me.

          Too early to tell how effective it is going to be.

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          • #6
            Originally posted by Mr incredible
            Having regard to the passage below I just wanted to ask "has anyone on here used the two together and how did they find it?


            "A possible synergism between yohimbine and ephedrine hasn't been thoroughly explored, and the information that exists is somewhat contradictory. In theory, they should work well together as yohimbine blocks one of the negative feedback mechanisms that would normally make ephedrine less effective. Cell culture studies confirm that yohimbine increases the lipolytic effects of beta(3) agonists (19). However, a study using rats indicated that yohimbine blocked the effects of the same beta(3) agonist, indicating that the two may antagonize each other (19). Additionally, a study on cardiovascular variables found that ephedrine and caffeine together were safe, but the addition of yohimbine may produce undesirable effects (20). So it is still unknown whether the combination of yohimbine and ephedrine produces any additional benefit, and whether it is justified by the potential dangers. "

            The above passage is taken from the link below
            http://www.uk-supplements.com/pg-art...les_id-69.html

            i dont care musch for yohimbine. makes me not feel right.

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