IGF-1 and Nolva

[ROCKETW19]

I don't think that it blocks the receptors guys, if recolection serves at the worst nolvadex reduces the amount of IGF your liver produces. Let me see if I can find those articles

steroids.com many years ago said that the use of nolva while on GH would supress gains due to the nolva binding and blockin the recptors. (that was just from memory not word for word)
anabolics 2005 have it in my hands right now says "tamoxifen on IGF-1 levels, demonstrating it to have a suppressive effect.
now by that study sayin it suppresses natural IGF-1 is enough for me to not take it. now your addin in a outside product that probably dosnt even work and addin to it by using nolva.(the part about IGF-1 suplementing not workin is just my opinion)

[pockethercules]

Rocket, I thought you were fixing to take IGF-1?

[ROCKETW19]

Rocket, I thought you were fixing to take IGF-1?

yes im gonna try it cuzz my guy is gonna give it to me for free! ive told him that shit dont work so i guess he wants to prove me wrong. either way i cant loose. but i would never pay a penny for it. these are just my opinions.

[pockethercules]

I know some guys that have taken it and they were satisfied with the results. I personally have never taken it so I can't tell you one way or the other. I am definitely interested in what you think of it when you try it. I was thinking about trying it this summer.

[kingj]

So if I were to run nolva when I'm taking the IGF what would happen.. am I not going to see any results? or does this just have effects on natural IGF?

[pockethercules]

According to Anabolics 2005 it will hinder your results. To quote. "When tamoxifen was given, GH and IGF-1 levels were notably suppressed" It goes on to say that IGF-1 levels are elevated when Testosterone was given while Nandrolone did not show the same characteristics. From reading this article it leads you to believe that it is estrogen that is responsible for the increase and decrease in GH and IGF levels. This also leads you to believe that any anti-estrogen will hinder the results you would get from GH and IGF. Now it does not say anything about binding to the GH and IGF receptors. Regardless it obviously will hurt your results so I would use only if necessary.

[Skyefire]

i dont save research after i read it! i read it on steroids.com many years ago and anabolics 2004 had the same thing. now can you post research that it dosnt? actully can you post research that your IGF-1 actully works??????

easy there bro, nolvadex does reduce the level but I am pretty sure that it had to do the nolvadex effect on the liver, it is an estrogen related issue I believe. I have not had a chance to look for it but there is a pretty good artical on this subject, some have even claimed that the suppressiong of the release of IGF (the liver converts other things into it if i remmber right) is what caused the lack of gains with nolvadex (that isn't likely, it more to do with the suppression of estrogen). Let me look around and find some better info.

[Skyefire]

steroids.com many years ago said that the use of nolva while on GH would supress gains due to the nolva binding and blockin the recptors. (that was just from memory not word for word)
anabolics 2005 have it in my hands right now says "tamoxifen on IGF-1 levels, demonstrating it to have a suppressive effect.
now by that study sayin it suppresses natural IGF-1 is enough for me to not take it. now your addin in a outside product that probably dosnt even work and addin to it by using nolva.(the part about IGF-1 suplementing not workin is just my opinion)

There is a big differnace between "demonstrating it to have a suppressive effect" and binding to the IGF receptor with the latter meaning that IGF should not be ran with nolvadex. Keeping the liver from releasing or converting IGF is a trade off with the drug. nothing, nothing is for free in this world. But it has long been known that nolvadex can reduce your gains somewhat. this is IMO a small price to pay for not getting bitch tits. But if you think about it why would nolvadex bind to the IGF sites when the IGF does not bind to the estrogen sites?

As for IGF not working well it has been shipping for a couple of years now (longer to a select few). If it was really just snake oil don't you think people would have noticed by now? It may not work for some, better for some then others and so on. As for studies there are several but there on mice, its just too new for there to be any humen studies or even studies done on higher test subjects. But there are too many happy customers to say that it doesn't work altogather.

[pockethercules]

I was not debating wether it blocks the receptor or not. I was just stating that anabolics 2005 did not mention it. I was just quoting the article. Regardless if it binds to the receptor or not the article makes you believe that it has a significant suppressive effect , for whatever reason, on GH and IGF-1 levels. That is a enough to not make me want to mix the two together if at all possible.

[ROCKETW19]

I was not debating wether it blocks the receptor or not. I was just stating that anabolics 2005 did not mention it. I was just quoting the article. Regardless if it binds to the receptor or not the article makes you believe that it has a significant suppressive effect , for whatever reason, on GH and IGF-1 levels. That is a enough to not make me want to mix the two together if at all possible.

i agree 100% i might have worded it wrong or something but the bottom line is i agree its not worth takin the chance. i know 2 people that i trust with what ever they say and they both have tryed IGF-1 a few time and both came back with i felt bloated thats it. even bouncer said it did nothing for him i dont know him but he dosnt seam like the bullshit kinda guy he sayes thing straight up. so thats 3 people i trust.

[pockethercules]

I'm probably going to try it in about a month, I'll let you know what I think. My first powerlifing meet will be in March so I will give it a try right before it to see if it does anything. it is a local meet so if it doesn't work it won't matter.

[RUI-Products]

okay so when using GH you are depending on the liver to produce the IGF. IF you are taking IGF with nolva through PCT there won't be any suppresion of Production. You will be supplying the IGF directly. You would see results. Why are you using nolva ....letro would be the better choice. IT increases igf levels by 27%.

[ROCKETW19]

I'm probably going to try it in about a month, I'll let you know what I think. My first powerlifing meet will be in March so I will give it a try right before it to see if it does anything. it is a local meet so if it doesn't work it won't matter.

are you gonna be on anything else? or just IGF-1? good luck in you meet.

[Shibby]

okay so when using GH you are depending on the liver to produce the IGF. IF you are taking IGF with nolva through PCT there won't be any suppresion of Production. You will be supplying the IGF directly. You would see results. Why are you using nolva ....letro would be the better choice. IT increases igf levels by 27%.

Maybe he wants to block the estrogen from binding, instead of inhibiting the production of it.

[pockethercules]

are you gonna be on anything else? or just IGF-1? good luck in you meet.

Yeah, test and tren. I know how I respond to that cycle. I should be able to tell if the IGF works. Oh and thanks! It is just going to be a tune-up meet.