Which is better

[Pheonix782]

Ok I've looked on here but I still don't have a concise answer as far as what is better T3/cytomel or T4 (Thyroxine)? I mean Thyroxine is basically converted into T3 but as far as Cytomel or T3 goes I mean does it stay in the body just as long or at most stays there a day? And Opinions, which is better and why? Preferences? Right now I'm about to start cutting and I'm curious as to effectiveness vs. results vs long term effects. I mean right now I'm on 50 mcg of levothyroxine bc of my thyroid...so will taking the T3 screw me up or should I just up my dosage? and by how much? Any help would be awesome, thanks!

[Mr I]

I find T3 a bit better (even when taking 4 x the mcg of t4), but both of them arn't all they are cracked up to be. T3 is a better combo generally because there are many compounds that slow your conversion of T4 to T3, thus making the T4 less effective; GH, Clen etc so if you take the T3 neat so to speak you avoid these risks.

I'm currently running T3 with my 2iu GH per day and it seems to combine well.

[Primal Instinct]

So you have a hypoactive thyroid then but your thyroid gland still works. I also take thyroid meds (levothroid 150mcgs each day) but then again, my thyroid died long ago from radiation. Mr Incredible is correct in his statements about T4 to T3 conversions. T3 is already converted whereas, T4 conversion takes place in the tissues.


One thing to consider when manipulating the body's thyroid levels is that thyroid levels are regulated in the body through a type of feedback loop involving the hypothalamus, the pituitary gland and the thyroid gland. TRH (thyrotropin releasing hormone) is released by the hypothalamus to the pituitary gland. In response, the pituitary gland sends TSH (thyroid stimulating hormone) to the thyroid gland. If levels are low, the pituitary calls for more T4/T3 to be manufactured and released by the thyroid gland. If levels are too high, the pituitary calls for a lesser amount of T4/T3 to be released by the thyroid. Since thyroid prduction is not an instantaneous process AND is regulated by the feedback loop discussed above, it takes several days to regulate natural thyroid hormone levels.


Just like when on a testosterone cycle, when one adds extraneous thyroid hormone to the human body, the body responds by decreasing natural production levels. Like I said, it can take several days (perhaps even a couple of weeks) to stabilize thyroid levels. So be careful not to crash your natural production system by using this stuff at higher than natural levels too long. Just like with a test crash, you might feel the thyroid crash after discontinuing the T4/T3 supplementation for a while. Energy levels decrease dramatically, cholesterol levels also increase in response to low thyroid levels, hair can get coarse and skin can get dry and flaky, even forgetfulness can occur from low thyroid levels. Oh, and the worst of it all- FAT gain! Perhaps tapering would be an effective startegy to regain natural thyroid production levels.


Maybe some of this info helps?

[Pheonix782]

Ok so if I go the T4 route, How much is enough?

[Mr I]

so we've established that T3 is more powerful but your going for the T4, ok, then do a search on T4 on this site and read all the info.