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Proviron. Why is this not talked about more?

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  • #31
    stickin my nose in agian sorry bouncer. but no you will not have any problems with progestrone gyno from a test proviron cycle! like we already talked about proviron is a mild anti-e so unless you are super prone to gyno i think you will be fine from the estrogen. if not you can add nolva with no harm. (probably only 10mgs needed)

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    • #32
      Originally posted by ROCKETW19
      stickin my nose in agian sorry bouncer. but no you will not have any problems with progestrone gyno from a test proviron cycle! like we already talked about proviron is a mild anti-e so unless you are super prone to gyno i think you will be fine from the estrogen. if not you can add nolva with no harm. (probably only 10mgs needed)
      My only concern is that proviron is DHT derived. Anything from DHT can turn into progesterone cant it? if it did, and i took nolv, it could actually make it worse if i understand correctly.

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      • #33
        Originally posted by THE BOUNCER
        My only concern is that proviron is DHT derived. Anything from DHT can turn into progesterone cant it? if it did, and i took nolv, it could actually make it worse if i understand correctly.
        Not dht compounds, nandrolone compounds like tren and deca are shown to create progesterone gyno. Proviron and test go together like nothing else.
        Last edited by beefcake; 02-12-07, 04:51 PM.

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        • #34
          Originally posted by THE BOUNCER
          My only concern is that proviron is DHT derived. Anything from DHT can turn into progesterone cant it? if it did, and i took nolv, it could actually make it worse if i understand correctly.
          the progestational activity is so low its almost considered none. i have used proviron many many times with tren even and never a problem unless i go to high on the tren but thats a different issue. the only problem you will have with a test proviron cycle is your girl is gonna be tired for you rubbin up on here every 10 minutes.

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          • #35
            Gyno shouldnt appear Bro, the proviron should take care of evertything...you should be fine.....unless you are really sensitive to estrogen.

            And Rocket Bro is right about proviron. And you could also add Tren to that statement (unless you are using high amounts of an aromatizating steroid with high amounts of Tren).

            In fact, I once was running a TestP and TrenA cycling and the titties started to get really sensitive. So I used the only thing I had on hand at that time, which was Nolva. After 4 days, the gyno disappeared.

            IMO, the main culprit for causing progesterone gyno is Decca or should I say the Nandrolone steroids.

            Actually, I believe, if my memory correct, it has been has been concluded that both nandrolone and several of its metabolites, do indeed activate the progesterone receptor and are altered by it.

            In fact, it has been (I had to make sure).......

            Clark SW, Sweet F, Warren JC., Synthesis and use of affinity-labeling steroids for interceptive purposes., Am J Obstet Gynecol 1975 Mar 15;121(6):864-73

            Hochberg RB, Hoyte RM, Rosner W., E-17 alpha-(2-[125I]iodovinyl)-19-nortestosterone: the synthesis of a gamma-emitting ligand for the progesterone receptor., Endocrinology 1985 Dec;117(6):2550-2

            Traish AM, Williams DF, Wotiz HH., Binding of (3H)7 alpha,17 alpha-dimethyl-19-nortestosterone (mibolerone) to progesterone receptors: comparison with binding of (3H)R5020 and (3H)ORG2058., Steroids 1986 Feb-Mar;47(2-3):157-73

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            • #36
              so why is it that Pro viron does nothing apparently anabolic to me yet Masteron yields great muscle growth results, at the dosages mentioned above 25-50mg provuiron and 200-400mg Masteron?

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              • #37
                Originally posted by Mr incredible
                so why is it that Pro viron does nothing apparently anabolic to me yet Masteron yields great muscle growth results, at the dosages mentioned above 25-50mg provuiron and 200-400mg Masteron?
                Quite odd. DHT binds to the androgen receptor better than anything, but isn't anabolic. Great for lowering SHBG, but not anabolic on it's own.

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                • #38
                  Originally posted by THE BOUNCER
                  Seems to me like Proviron should be used during any testosterone based cycle for various reasons. Here are a few cut and pasted paragraphs about provirion. I put a few real points of interest in bold for those who wont take the time to read.


                  Proviron has four distinct uses in the world of bodybuilding. The first being the result of its structure. It is 5-alpha reduced and not capable of forming estrogen, yet it nonetheless has a much higher affinity for the aromatase enzyme (which converts testosterone to estrogen) than testosterone does. That means in administering it with testosterone or another aromatizable compound, it prevents estrogen build-up because it binds to the aromatase enzyme very strongly, thereby preventing these steroids from interacting with it and forming estrogen. So Mesterolone use has the extreme benefit of reducing estrogenic side-effects and water retention noted with other steroids, and as such still help to provide mostly lean gains. Its also been suggested that it may actually downgrade the actual estrogen receptor making it doubly effective at reducing circulating estrogen levels.

                  The second use is in enhancing the potency of testosterone. Testosterone in the body at normal physiological levels is mostly inactive. As much as 97 or 98 percent of testosterone in that amount is bound to sex hormone binding globulin (SHBG) and albumin, two proteins. In such a form testosterone is mostly inactive. But as with the aromatase enzyme, DHT has a higher affinity for these proteins than testosterone does, so when administered simultaneously the mesterolone will attach to the SHBG and albumin, leaving larger amounts of free testosterone to mediate anabolic activities such as protein synthesis. Another way in which it helps to increase gains. Its also another part of the equation that makes it ineffective on its own, as binding to these proteins too, would render it a non-issue at the androgen receptor.

                  Thirdly, mesterolone is added in pre-contest phases to increase a distinct hardness and muscle density. Probably due to its reduction in circulating estrogen, perhaps due to the downregulating of the estrogen receptor in muscle tissue, it decreases the total water build-up of the body giving its user a much leaner look, and a visual effect of possessing "harder" muscles with more cuts and striations. Proviron is often used as a last-minute secret by a lot of bodybuilders and both actors and models have used it time and again to deliver top shape day in day out, when needed. Like the other methylated DHT compound, drostanolone, mesterolone is particularly potent in achieving this feat.

                  Lastly Proviron is used during a cycle of certain hormones such as nandrolone, with a distinct lack of androgenic nature, or perhaps 5-alpha reduced hormones that don't have the same affinities as DHT does. Such compounds, thinking of trenbolone, nandrolone and such in particular, have been known to decrease libido. Limiting the athlete to perform sexually being the logical result. DHT plays a key role in this process and is therefore administered in conjunction with such steroids to ease or relieve this annoying side-effect. Proviron is also commonly prescribed by doctors to people with low levels of testosterone, or patients with chronic impotence. Its not perceived as a powerful anabolic, but it gets the job done equally well if not better than other anabolic steroids making it a favorite in medical practices due to its lower chance of abuse.

                  Mesterolone is generally well liked nonetheless as it delivers very few side-effects in men. In high doses it can cause some virilization symptoms in women. But because of the high level of deactivation and pre-destination in the system (albumin, SHBG, 3bHSD, aromatase) quite a lot of it, if not all simply never reaches the androgen receptor where it would cause anabolic effects, but also side-effects. So its relatively safe. Doses between 25 and 250 mg per day are used with no adverse effects. 50 mg per day is usually sufficient to be effective in each of the four cases we mentioned up above, so going higher really isn't necessary. Unlike what some suggest or believe, its not advised that Proviron be used when not used in conjunction with another steroid, as it too is quite suppressive of natural testosterone, leading to all sorts of future complications upon discontinuation. Ranging from loss of libido or erectile dysfunction all the way up to infertility. One would not be aware of such dangers because Proviron fulfills most of the functions of normal levels of testosterone.

                  Let´s delve into some of the positive points of this drug before we go any farther. Androgen Receptors are found in fat cells as well as muscle cells(5), and whilethey act on the AR in muscle cells to promote growth, they also act directly on the AR in fat cells to affect fat burning.(9)(3) The stronger the androgen binds to the A.R, the higher the lipolytic (fat burning) effect on adipose (fat)tissue(6)(2). As if that´s not enough good news, some steroids (notably, testosterone) even increase the numbers of A.R. in muscle and fat (9)(7). Thus, if you are taking a simple stack of proviron and testosterone, you´ll have more of the test you shoot as free testosterone floating around building muscle (compliments of the Proviron), more androgen receptors to be bound to (compliments of your testosterone) by your Proviron, thus causing more fat loss. Testosterone and Proviron are a very nice synergistic stack, pretty nearly an "ideal" stack of an oral and injectable, because both drugs will actually act to enhance the effect of the other.

                  So what we have here is a steroid which can basically make other steroids more effective by preventing their conversion into estrogen, as well as increasing the amount of circulating free testosterone in your body. This of course all provides a more hardened and quality look to muscles. Proviron is very much a "synergistic" drug in this respect, and it´s inclusion in any cycle would definitely make all of the other steroids perform better, and provide better gains. This is all compounded by the fact that proviron is a very lipolytic (fat-burning) drug.


                  Proviron is a great item. I like it in all cycles. Super for libido.

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                  • #39
                    Originally posted by Mr incredible
                    so why is it that Pro viron does nothing apparently anabolic to me yet Masteron yields great muscle growth results, at the dosages mentioned above 25-50mg provuiron and 200-400mg Masteron?
                    If I was just to make an assumption, based on know facts, I would have to say because it an injectable and it has a propionate ester attached.

                    Which means...... 1 - constant state of hormone (masteron) level.
                    2 - its flowing 24/7 through your system until you go off and then some.

                    Where Proviron clears the system quickly.....I want to say 6 hrs, but dont quote me on it.

                    Thats why you need to spread out your dosage (unless using alone) of an oral hormone. But even then, its not as good as the injectable form.

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                    • #40
                      on that basis, I wish they'd bring out injectable anavar, that would be the bomb, run with masteron enanth!

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                      • #41
                        Injectable Anavar would be basically the same as oral because there is no ester attached to it.

                        Also, masterone has an Propionate ester not a Enanthate.

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                        • #42
                          Originally posted by The Iron Bull
                          Injectable Anavar would be basically the same as oral because there is no ester attached to it.

                          Also, masterone has an Propionate ester not a Enanthate.
                          I bought some british dragon and used it not long ago, it said enanthate same as their long tren and worked well but maybe they were lying then, don't know why they would though. Surely you can easily change the ester, thats why you can get test in; propionate, deconoate, cypoinate, enanthate etc etc

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                          • #43
                            Originally posted by The Iron Bull
                            Injectable Anavar would be basically the same as oral because there is no ester attached to it.

                            Also, masterone has an Propionate ester not a Enanthate.
                            ive seen it in enant. my source has it!

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                            • #44
                              LOL....you right Bros. My bad.

                              :dunno: I dont have a fraking clue what I was thinking about :sleep:

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                              • #45
                                Originally posted by The Iron Bull
                                LOL....you right Bros. My bad.

                                :dunno: I dont have a fraking clue what I was thinking about :sleep:
                                not trying to be stupid but you haven't seen drostanolone enanthate powder before? its rare but I have both bought it and made it before for myself.

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