TargeX Any Good?

[TheReelOnes]

Have any of you heard about the stuff called TargeX? Seems to be a lot of chatter on other boards but no concrete results from its use. That statement in itself might be my answer but never the less.......For inquiring minds.

[latin22]

All I have heard is that it is Glycyrrhetinic acid and when applied to the skin, can reduce the thickness of subcutaneous fat.I don't know anybody using it just what I have read

[Bouncer]

Never heard of it. Is it a steroid or what?

[alwaysgrowing]

ULTIMATE TOPICAL FAT BURNER!
TargeX TDS (NEW FORMULA!)


Glycyrrhetinic acid is the primary ingredient in Targex. It is actually found in licorice, and when applied to the skin, can reduce the thickness of subcutaneous fat. In this case, the mechanism of action is mediated by the catabolic hormone known as cortisol. This hormone is involved in both the distribution as well as the deposition of fat.Cortisol, in turn is regulated by the activity of an enzyme which Glycyrrhetinic acid (the active ingredient in Targex) blocks. This reduces the ability of cortisol to regulate fat cells, resulting in an overall loss of bodyfat to the area the cream is applied to.

In a clinical study, the effect of topical Glycyrrhetinic cream was evaluated. In this study, measurements of thigh fat, before and after 1 month of treatment with the cream were taken. In both areas (circumference and the fat layer thickness) the thighs receiving the cream had significantly lower levels of fat.

Hence, this type of cream would appear to be a potent lipolytic (fat burning) agent. Also, it is important to note that this compound is very safe, as the full study mentioned previously states that that there was absolutely no change in plasma cortisol, blood pressure, or aldosterone.

The primary ingredient in that study (Glycyrrhetinic acid) is also the primary ingredient found in Targex; this is actually the brand name of the original version of these types of products. Typically it is applied to specific sites, to produce localized fat-loss wherever it is applied. The typical Targex user has experienced significant reductions in body fat when it was applied to site-specific areas, and was used in combination with a proper diet, training, and cardio.

[alwaysgrowing]

http://clinicaltrials.gov/ct/show/NCT00384384;?order=46

Purpose
Background: 18B Glycyrrhetinic acid (active compound of Licorice) decreases serum potassium via enhanced renal potassium loss in healthy individuals and thereby inducing renal sodium retention and arterial hypertension.In dialysis patients this mechanism is disturbed and compensatory intestinal potassium secretion is enhanced. 18B Glycyrrhetinic acid is an inhibitor of 11B Hydroxysteroid dehydrogenase type 1 (11b HSD1). Inhibition of 11 b HSD1 offers a novel potential therapy to lower intracellular cortisol concentrations and thereby enhance insulin sensitivity.

Hypothesis: Glycyrrhetinic acid decreases serum potassium by enhanced intestinal excretion in dialysis patients and increases insulin sensivity by inhibition of 11b HSD

Methods: double blind, 6 month cross over trial comparing oral 18b Glycyrrhetinic acid with placebo in 24 nondiabetic dialysis patients.

Endpoints: predialytic serum potassium levels, insuline sensitivity assessed by fasting glucose and fasting insulin concentrations

[Bouncer]

Sounds interesting. Is this a new compound or has it been around?

[alwaysgrowing]

im not sure. some place is sellign it as a research chemical. another place is having it imported straight from china.

[Ashop]

sounds interesting but ive not seen a topical fat remover yet.

[TheReelOnes]

Thanks for all your responses. I am going to buy some from a reasearch company given the cost is relatively low. We will let you know how the experiment goes.

[Bouncer]

Thanks for all your responses. I am going to buy some from a reasearch company given the cost is relatively low. We will let you know how the experiment goes.

i would hold off on everything given your resent blood work results. be safe bro.

[alwaysgrowing]

my friend has offered to be a lab rat. he is going to the bahamas on spring break. so he ordered it yesterday. he is starting his diet the day after christmas. i'll keep you all updated

[TheReelOnes]

I have stopped everything foreign for now and will save the TARGEX for my next cutting cycle.

BTW think I got scammed on my last junk order. Will advise on seperate post.

[Bouncer]

I have stopped everything foreign for now and will save the TARGEX for my next cutting cycle.

BTW think I got scammed on my last junk order. Will advise on seperate post.

good call

[alwaysgrowing]

this stuff i'm undecided on. my friend who has been using it, thinks it is working. he has lost some weight whie on it, but he has also been strict with his diet. it has some alcohol in it, so it may just deplete the water from his skin. his abs not lookiong too bad though