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Now I'm not a big fan of multi ester tests but I have used them in the past ( sust ) . I have decided to give axio another try...I think I last tried them when they first came out. Anyway I have done two 3/4ml shots since thursday last week of there sustaplex 325 ( old white lable & couterfeit cap ) and I have been in bed for the last 24hrs with test flue...I am just starting to feel better. Based on past experience with test flue I know this comes from a build up of BB or BA in your system. Just did a smell an taste test and sure eneough its strong enough to make your eyes water...smells more like BB. My injection sites are very sore aswell. Anyone else have bad experience with this product?
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Actually test flu is caused by a metabolite of testosterone, not BA, however can cause injection site pain.
Etiocholanolone is believed to produce fever and flu-like aches and pains because it induces the systemic release of Interleukin-1, a powerful proinflammatory cytokine:
Pyrogenicity of etiocholanolone and interleukin-1 in New and Old World Monkeys.
Steinetz BG, Randolph C, Werner R, Mahoney CJ.
New York University Medical Center, Laboratory for Experimental Medicine and Surgery in Primates, Tuxedo 10987, USA. [email protected]
Etiocholanolone (5beta-androstan-3alpha-ol-17-one; designated E) is one of the major products of metabolism of testosterone and androstenedione (androst-4-ene-3,17-dione) in many mammalian species, including humans. E and several other 5beta-reduced steroids have been found to induce fever in humans. The pyrogenic effect of these steroids has been shown to be due to the release of interleukin-1 (IL-1) from the leukocytes that are mobilized in response to the steroid injections. Old World Monkeys such as Rhesus monkeys (Macaca mu/atta), metabolize androgens similarly to humans, and E is a normal metabolite. However, New World Monkeys such as Squirrel monkeys (Saimiri sciureus), lack hepatic 5alpha- and 5beta-steroid reductases and excrete androgens primarily in an unaltered state; E is not produced. Therefore, we postulate that Squirrel monkeys likewise may have lost the ability to respond to 17-ketosteroids such as E. To test this hypothesis, adult male Rhesus and Squirrel monkeys were treated with E, and their rectal temperatures were recorded over a 24-hr period. Rhesus monkeys exhibited a rise of up to 3 degrees F following E injection. Squirrel monkeys, on the other hand, did not exhibit any increase in rectal temperature over the 24-hr period, even when doses up to 250 times the effective human dose were used. However, both species responded to injected IL-1alpha with a robust increase in rectal temperature. The data show that E is pyrogenic in Rhesus, but not Squirrel monkeys. The findings support the notion that injected E may induce release of IL-1 in Rhesus monkeys, but not in Squirrel monkeys. -
interesting. I just firgured from experimenting in the past with high doses and high mg/ml that it was caused by a build up of ba or bb . If thats the case then diluting the shot probably wouldn't make any difference?Comment
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True, but in most cases dilution will reduce inflammation in the injection area.Originally posted by overdose View Post
It seems that after a few weeks your body stops reacting so harshly to the
Etiocholanolone.Comment
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AH...probably reacting this way becaues I have taken many months off. Thanks for your input.Comment
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lifts , could it be the powders the supplier is using ?
just read in md that they tested a few ugs - results will be in next mag -
they are finding high concentrations of metals in some of the products . some ug labs came out with great labs but others show high concentrations of metals -
have to say i am using test enanthate right now that cripples me - never fucking felt this bad in my life beforeComment
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I have not tried the brand you are using and I was not knocked to bed But the Sust i have used always caused painful injection sites and I did not feel well the first few weeks. Thats the reason I now go with cypComment
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sust seems to be painful in both human grade and UG. enath and cyp dont bother me but sust, the times i have used it has been a bitch.
house, if you feel that bad, your body is telling you something is wrong with the gear etc.. might want to listen to your body.Comment
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just found a post on another board...the user posted an Email he received back from this lab . I guess there has been some problems this year with quality with some batches...the lab also addessed the prob with painful gear in this Email, stating that they had an issue with high BA levels in the gear.
I agree. I usually stay away from UG stuff...the pain i can deal with its the test flue I hate.house, if you feel that bad, your body is telling you something is wrong with the gear etc.. might want to listen to your body
Just because I'm a cheap bastard I'm going to try another shot cut with some oil..if i end up with test flue i guess I'll have to chuck it.Comment
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do you have the email bro. can you post it. block out any info personal info of course.Originally posted by overdose View PostComment
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i just read several posts aswell on axio - def off my list of places to tryOriginally posted by overdose View PostComment
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