Originally posted by Alin
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gh , ghrp and cjc 1295
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BOUNCER , have to say was worse hunger pains i ever felt .... made me really uncomfortable but i just lived with it because of results ... telling you bro i would eat and 15 minutes later feel like i have not eaten in days ...Originally posted by THE BOUNCER View Posthow bad is the hunger on ghrp-6? unmanageable?
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so in other words it just makes your body use nutrients all day! i will eat 500 chickens a day then! :rofl:Originally posted by bigscott View PostBOUNCER , have to say was worse hunger pains i ever felt .... made me really uncomfortable but i just lived with it because of results ... telling you bro i would eat and 15 minutes later feel like i have not eaten in days ...
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This Article is now out of date. CJC-1295 is counterproductive should not be used because of its effect on GH "bleed".Originally posted by liftsiron View PostYou can inject twice per week provided you get the Dac, some peptide people don't sell the dac version. I think minimum would be about 500mcgs 2X per week.
I ran it with GHRP6 because peeps that I know said that's the best way to run it. GHRP6 is dirt cheap anyhow. I got hgh like results only far faster than with hgh. Much cheaper to. Shit seemed to help the joints to.
Partial explanation (Oct 21, 2009)
"Cell-to-cell communication is also likely to reflect the density and proximity of adjacent cells as GH responsiveness (but not sensitivity) to GHRH is enhanced at higher densities and basal GH release is greatest at low densities."
"Cell-to-cell contact may therefore affect the cellular integrity of somatotrophs because GH synthesis or secretory granule storage may be better maintained in high density cell concentration then in low-density concentrations." - Growth Hormone, Stephen Harvey
What happens is cells in the pituitary communicate. They self organize and create a firing network for coordinated growth hormone release. This communication creates a high density of GH releasing cells. They are in close proximity through their communicatory network. The cells have specific spatial relationships that may be modulated by peripheral endocrines. These include sex steroids, thyroid hormones, glucorticoids and even the pancreatic and gut hormones. Their spatial relationship is also effected by physiological state such as nutrient status, age and pregnancy.
As a quick example, corticotroph, thyrotrophs and folliculostellate cells are in close proximity to somatotrophs and communicate with them through gap junctions (almost like just reaching out and touching signaling). They have the potential to effect and be effected by their neighbors.
What happens when you have GHRH always around is you force these somatotrophs to release GH because they are sensitive to the GHRH binding to them and effecting release. By constantly occupying you are preventing them from coordinating with surrounding cell populations. You force these cells to act as low density subpopulations. Basal GH release is greatest when you can disperse the spatial relationship between somatotrophs and that is what an always on GHRH will do.
CJC-1295 as an always on GHRH will force upon somatotrophs loner behavior with a single constant chore. This reduces GH responsiveness as this only occurs when somatotrophs can communicate, self organize and maintain social relationships with the surrounding community. These types of social somatotrophs are better able to make and store GH then the loner cells.
So CJC-1295 seems to disperse somatotrophs and enslave them getting less from them then if it had just let them congregate in towns and cities.
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According to the author the hyphotalamus needs a break from the pulsations created by the GHRP and GHRH (CJC1295 w/ DAC the culprit) if it continues within the day then a term called "GH bleeding" happens which is not productive.
Just sharing what I read guys...
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So are you saying don't use cjc at the same time as ghrp or don't use cjc at all, either way it seems to be working for bigscottOriginally posted by ken69 View PostAccording to the author the hyphotalamus needs a break from the pulsations created by the GHRP and GHRH (CJC1295 w/ DAC the culprit) if it continues within the day then a term called "GH bleeding" happens which is not productive.
Just sharing what I read guys...
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cjc1295 is actually miss labeled in most cases. "CJC1295" without DAC is just GHRH. the "DAC" added to it makes it CJC1295. they are saying now that you DONT want the DAC because it causes GH bleed and therefor your body will desensitize quickly.Originally posted by Mr incredible View PostSo are you saying don't use cjc at the same time as ghrp or don't use cjc at all, either way it seems to be working for bigscott
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Well since I have some coming, would it be best to just use it less regular eg once per week, giving the hypothalamus chance to recover ?Originally posted by THE BOUNCER View Postcjc1295 is actually miss labeled in most cases. "CJC1295" without DAC is just GHRH. the "DAC" added to it makes it CJC1295. they are saying now that you DONT want the DAC because it causes GH bleed and therefor your body will desensitize quickly.
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i really dont know as i stopped researching the cjc1295 after i read the shit about gh bleed and how 95% of it is not cjc because it dosent have DAC.Originally posted by Mr incredible View PostWell since I have some coming, would it be best to just use it less regular eg once per week, giving the hypothalamus chance to recover ?
GHRP seemed like the better option.
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