Questions for those who have used IGF - Thinking of giving it a try.

[Bouncer]

BOUNCER , do not reconstitute with bac ... the peptide will slowly die rendering it useless in as little as a 24 to 48 hour period and complaints that it doesnt work surface :)

.. reconstitute with acetic acid .. the nacl solution is used before injection i use bac water .. pull in atleast 1 to 2 iu bac water then pull in your 60 mcgs of igf13 the bac will help dilute the acetic acid you reconstituted the igf13 with .. ... do not do it sub q !! the acetic acid can create painful welts .. try it without the bac water and you will not do it again lol ... its burns

post w is best time ... run it 4 weeks on 4 weeks off


make sure you pull in bac water before the igf13 so you can use the water to completely clear the pin of all igf13

cool thanks!

where do i get acetic acid? i dont think RUI has it.

also, how much acetic acid do i put in the 1mg of lyophilized igf lr3?

[bigscott]

Well I always did with BAC water and seemed fine...didn't know about the rendering part though.

yup -- mixing it with just bac water its good for 48 hours . the peptide cannot survive ....

[bigscott]

cool thanks!

where do i get acetic acid? i dont think RUI has it.

also, how much acetic acid do i put in the 1mg of lyophilized igf lr3?

thats 1000 mcgs so 1 ml of acetic acid B

[bigscott]

cool thanks!

where do i get acetic acid? i dont think RUI has it.

also, how much acetic acid do i put in the 1mg of lyophilized igf lr3?

the aa should really come with it !!! you can find it here though Acetic Acid its at proper ph which is important

[Bouncer]

scott, what do you think about this idea.

mix the igf with BAC water, load up a bunch of slin pins and keep them in the freezer?

will the igf mixed with BAC stored in the freezer last longer?

just seems like a pain in the ass to mix it with fucken AA and then have to add in bac to take away the sting.

hell, i just read an article saying the AA can actually harm the IGF!! lol

[Bouncer]

the aa should really come with it !!! you can find it here though Acetic Acid its at proper ph which is important

well it says "lyophilized" on the RUI site so i assume it has no AA correct?

[bigscott]

well it says "lyophilized" on the RUI site so i assume it has no AA correct?

yes but most company's will send the right amount of aa with your purchase ... imo they all should ...

B , it is a pain in the ass but mix with aa bro ... otherwise it will only have even frozen a shelf life of 48 hours

[ROCKETW19]

scott, what do you think about this idea.

mix the igf with BAC water, load up a bunch of slin pins and keep them in the freezer?

will the igf mixed with BAC stored in the freezer last longer?

just seems like a pain in the ass to mix it with fucken AA and then have to add in bac to take away the sting.

hell, i just read an article saying the AA can actually harm the IGF!! lol

Im not scott but I think that is a bad idea. I am not even sure you can freeze it with out harming the amino acid chain?

Make sure the AA is .6% ph balance or it will kill the igf. I have never seen anyone sell igf without AA. If you cant find it I can look up the way to make it its simple using vinegar but personaly I dont trust myself,lol.

[Bouncer]

Good read, answer from a scientist in the field.


"Ok guys I have been reading every experts write up in IGF-1 and I still can't get a definitive answer on reconstitution. Everybody seems to say to use BA or acetic acid. Which is it?"


"It depends on how IGF-1 was made and what if any buffer (i.e. base) is present.

The reconstitution process is designed to create a stable pH or isoelectric point for that peptide so that protons don't move from one amino acid in the chain to another. If they do this they eventually degrade much of the peptide chain.

Every peptide has its own ideal ph or isolectric point (stable point) which is kind of just the sum of its parts. Each amino acid has specific properties. Some are acidic, some basic, some water loving, some water hating, etc. The peptide chain composed of all these amino acids takes on the ideal ph based on the sum of all these different amino acid characteristics.

So IGF-1 being a long-chain has an ideal environment in which it is stable. That really is the pH and it is stable because protons from atoms that make up the amino acids are happy to stay where they are.

Change the ideal environment and movement occurs.

So reconstitution is about finding the right environment and holding it.

Now the best way to hold the environment is to have a base and an acid present. The base has a pH on one end of the scale and the acid the other. Choosing a proper base (and amount) will allow a solution to "meet in the middle" when the two are introduced together.

So for IGF-1 LR3 this "meet in the middle" occurs with acetate (a base) and acetic acid (a weak acid). Now IF there is no acetate present because the maker did not put it in (or you failed to ) reconstituting w/ acetic acid will make the environment too acidic and IGF-1 LR3 will experience depronation and degrade rapidly. So in a situation where there is an adequate base present such as acetate, you want to use acetic acid.

Now IF no base is added, you do not want to add an acid. Reconstituting with sterile water will give a pH of 4-7. Bacteriostatic water has a pH around 5. This is not a bad environment for IGF-1. However the trick is getting it to hold. So although the environment may initially be close to ideal for IGF-1, will it be weeks from now, months or years from now. Studies show that with certain acid/base mixtures with something like Human or Bovine Serum Albumin added to reduce aggregation the peptide can be stable for months to years in reconstituted form.

This is not the case with water.

The second degradation determinant besides solution is temperature. In general the colder the temperature the less degradation that will occur. Some very hot temperatures can degrade a peptide significantly w/in 24 hours while refrigerated temps can show low or no degradation a month later.

Anyway I hope this helps improve your understanding. I would say "know your IGF-1 LR3 and how it is made, but I doubt even your retailer knows"."

[Bouncer]

does it matter post workout if you take the shot before or after your shake?

[Bouncer]

I did it several ways bro...What I liked best was when I woke up and before working out...You will enjoy the warmth and pump all day...

yea but lr3 is just once a day shot.

most people say to take it post workout but they never mention if that means before or after the shake or if that even matters.

[ROCKETW19]

yea but lr3 is just once a day shot.

most people say to take it post workout but they never mention if that means before or after the shake or if that even matters.

Ya I shoot then drink shake. I never read anywhere that it mattered.