Gyno

[Bouncer]

Tamox with a progestin drug is a no no from what I was always told.

[StanG]

Tamox with a progestin drug is a no no from what I was always told.

I know Bounce but thats rubbish. Tamox causes a slight up-regulation in the PGR receptor for approx 2 weeks, after which it actually changes to a down-regulation in the PGR receptor.
2 Things are important to note, (1) the up-regulation it causes has no clinical significance what so ever it is so minuscule & (2) after 2 weeks there is an actual down-regulation in the PGR receptor.
I really wish that one would just die. Also if you are really concerned, use Raloxifene, it doesn't have any effect at all on the PGR receptor and is actually more effective at preventing and or treating gyno anyway..

[Bouncer]

Gyno can be a strange and often impossible thing to understand.

For example a few years ago I ran something like test E @ 300mgs E5D and Tren E @ super low dose 100mgs E5D. On this cycle I started to develop gyno so I jumped on letro and even that would not get rid of my puffy sore nips. Had to stop the cycle and gyno disappeared.

Fast forward to today and I'm running over twice the dose of test and over 200mgs of Deca and yet I'm having no gyno issue on Adex.

One would think that if I got gyno on letro from a mild cycle that I should definitely have gyno from a higher dose cycle on Adex.

Makes no sense to me.

[StanG]

Gyno can be a strange and often impossible thing to understand.

For example a few years ago I ran something like test E @ 300mgs E5D and Tren E @ super low dose 100mgs E5D. On this cycle I started to develop gyno so I jumped on letro and even that would not get rid of my puffy sore nips. Had to stop the cycle and gyno disappeared.

Fast forward to today and I'm running over twice the dose of test and over 200mgs of Deca and yet I'm having no gyno issue on Adex.

One would think that if I got gyno on letro from a mild cycle that I should definitely have gyno from a higher dose cycle on Adex.

Makes no sense to me.

I agree, it can be tricky.
It not only can come down to hormone levels but hormonal ratios as well. That can make it really tricky as you can get blood work and your e2 can appear to be within range, yet you still have gyno issues. If you don't have a comprehensive hormone panel you cannot compare properly your androgen/estrogen ratio or factor in PGR or PRL levels and the impact they are or may be having.
The one constant, and it really saves all, is that if no e2 can reach the breast tissue gyno cannot grow or form. This means that Raloxifene really will serve you in any and all gyno scenarios. IMO it should really be the go too when it comes to gyno and then an ai can secondarily manage e2 if need be, or a DA if prolactin is an issue, etc.

[Bouncer]

Good to know. In that case Chadd, my vote goes towards you trying raloxifene.

What should his dose be guys? Should he stay on Adex or drop it and jump on ralox?

[StanG]

Good to know. In that case Chadd, my vote goes towards you trying raloxifene.

What should his dose be guys? Should he stay on Adex or drop it and jump on ralox?

IMO he should get blood work and whether he continues with dex or not depends on his e2 levels. If e2 is in range he should continue what he is doing and add Ralox. Since he already has a gyno issue he should front-load ralox for one week at 60mg/day and then after week one drop it to 30mg/day.
That's my opinion/suggestion.

Either way Chadd, whatever you do please keep us posted on your course of action and the outcome. This can help many people.

[Bouncer]

So basically it's not always that someone is more "sensative" to gyno, it's that some people ratios get more out of whack than others.

I know I'm overly simplifying it but that's the basic idea right?

[StanG]

So basically it's not always that someone is more "sensative" to gyno, it's that some people ratios get more out of whack than others.

I know I'm overly simplifying it but that's the basic idea right?

I think I would agree with that. I think when people refer to themselves as "gyno prone" or refer to someone as "gyno prone" that actually translates to more of a propensity towards hormonal imbalance than someone who we would consider "normal", yes.

[wheyman]

I had a battle with gyno a couple years ago. Nothing I did ever helped it. I finally went to the doc and played it off like something strange and sensitive near my nipple. They ended up removing it then told me it was gyno.

If Bouncer's recommendations don't work, and you have to have it surgically removed, make sure you don't even mention gyno. For some reason I remember thinking there could be insurance coverage issues if it's predetermined it's gyno. I could be wrong though.

[Bouncer]

I had a battle with gyno a couple years ago. Nothing I did ever helped it. I finally went to the doc and played it off like something strange and sensitive near my nipple. They ended up removing it then told me it was gyno.

If Bouncer's recommendations don't work, and you have to have it surgically removed, make sure you don't even mention gyno. For some reason I remember thinking there could be insurance coverage issues if it's predetermined it's gyno. I could be wrong though.

Did it leave a dent or impression? I'd be worried the surgery itself would fuck up the look of my chest.

[wheyman]

Did it leave a dent or impression? I'd be worried the surgery itself would fuck up the look of my chest.

I have small scar near my nip. There is also a small dent where the breast tissue was removed, but it didn't effect the shape of my muscle. IN fact, when I lean out it looks normal.

[Bouncer]

What's the plan of attack Chadd? You still growing boobies or what?

[FrankTheTank55]

Here's some good info. I have been using aromasin during cycles and Nolvadex post cycle. I don't understand why somebody would use it during their cycle, it doesn't stop the production of estrogen.

https://www.eroids.com/forum/steroid...ex-anastrozole

[chuckz28]

Here's some good info. I have been using aromasin during cycles and Nolvadex post cycle. I don't understand why somebody would use it during their cycle, it doesn't stop the production of estrogen.

https://www.eroids.com/forum/steroid...ex-anastrozole

Nolva and Raloxifene will prevent the estrogen in your body from binding to the receptors in breast tissue.

[FrankTheTank55]

Nolva and Raloxifene will prevent the estrogen in your body from binding to the receptors in breast tissue.

Yeah but you're gonna still be producing it. So you're gonna have a ton of estrogen just floating around and once you stop that nolvadex you're gonna get hit with it all.

Take an AI during the cycle and keep the estrogen down completely.