Tweet
At the end of this text will appeal from me to you, please read it.
This interview was done months ago (and some members of the forum know it), and I didn't put it on yet Rado has not passed their tests. Now it's not affect anything, and I want to publish it here.
Questions answers Alexander, a leading specialist company Inffarm.
How is the gh test in the lab?
We check not only gh, but also any other substance that produce for other companies. Our review includes 3 stages:
1) Chromatography by itself, this test may not be reliable. We have a results table - but the results are a variety of factors. Therefore, we conduct this test for one purpose only - to confirm the purity of the substance.
2) Chromatography in comparison with a benchmark - for this test we have substances from other manufacturers or if the customer provides samples - we compare our stuff with the sample. If we are talking about gh, we use a standarts of Omnitrope, Jintropin, Rastan, Genotropin and Norditropin. If the results of this test show that our substance is identical with the standards, it is allowed for the following tests.
3) a Blind comparison test - Passing this test we use an independent lab - SIL'verfarm. We select the substance and standarts in the same containers and send them for testing. Where what kind of material knows only special person from the laboratory conducting the tests. After receiving the results, if the substances in all samples showed the same results - we can prepare the documents (based on the findings of an independent laboratory), and consider your job done - we made the right substance with the desired purity.
It's great. But as an ordinary person to understand what his original work GH?
I think to understand good or bad gh you use you need to pass some tests. Because each test separately may not show the truth.
1) growth Hormone, Serum - an excellent test. But one can not be reliable. As the different organisms are different figures. Everyone has different metabolism and for reliable peak STG you need to pass several tests for several hours. As a confirmation of my words you can insert a link to the user manual Genotropin, section "PHARMACOKINETICS" https://www.accessdata.fda.gov/drugs...280s057lbl.pdf .
As you can read there - the spread of the results depends on many factors.
2) IGF-1 is a great test, but IGF can be "bind" IGFBP-3. IGFBP-3 is a peptide involved in the regulation of cell growth. It binds with the same affinity as IGF-1 and IGF-2. So it may be that IGF is low, while IGFBP-3 rolls.
For greater clarity, I can compare it how SHBG can "bind" testosterone and makes it inactive.
3) IGFBP-3 is also a great test, but as well as the other could not be reliable. As the cells of the liver GH should cause rise in IGF. For example if you have been taking oral AAS or any other drugs - it can greatly affect the results of the IGF. In fact any load on the liver may change the outcome of the IGF. For example for people who do not receive a high level of IGF in the treatment of growth hormone, used drug Increlex.
There is an opinion in the forums that 1IU GH should give +100 IGF-1 after 10-14 days, it seems to be true?
If so, I will start to use 15IU a day, I really want to see 1500 IGF :).
You need to understand that GH does not contain the IGF, it's just 191аа. IGF-1 is what should make your body more specifically the liver. This indicator is influenced by many factors - metabolism, mode, load on the liver health and susceptibility to the drug, and still a lot of factors.
Let's go back to the official instructions from Pfizer - they do not indicate possible values. Description of the IGF is reduced to a single phrase:
"During therapy, the dose should be decreased if required by the
occurrence of adverse events and/or serum IGF-I levels above the age - and gender-specific
normal range. Maintenance dosages vary considerably from person to person.".
If we translate this sentence into ordinary language it sounds like "who the fuck knows what will be there, everyone is different".
But how do you recommend to pass the tests?
I am a doctor and a scientist, I can't recommend people to conduct experiments on themselves without the supervision of specialists. But I can tell you like it was for me.
2 weeks before the test to stop using any other gh (that would not get "background"), any other drugs (if not prescribed by a physician) and started the diet and sleep.
The first day or 10IU.
The second day (Serum test) 1IU per 10 kg of body weight.
4 days 1IU per 10 kg of weight.
5 days 4IU
11 days, I would have passed the IGF-1 and IGFBP-3 with different time interval. And give them every day because I'm not important "snapshot" picture, I need to obtain the dynamics of the processes in my body.
This interview was done months ago (and some members of the forum know it), and I didn't put it on yet Rado has not passed their tests. Now it's not affect anything, and I want to publish it here.
Questions answers Alexander, a leading specialist company Inffarm.
How is the gh test in the lab?
We check not only gh, but also any other substance that produce for other companies. Our review includes 3 stages:
1) Chromatography by itself, this test may not be reliable. We have a results table - but the results are a variety of factors. Therefore, we conduct this test for one purpose only - to confirm the purity of the substance.
2) Chromatography in comparison with a benchmark - for this test we have substances from other manufacturers or if the customer provides samples - we compare our stuff with the sample. If we are talking about gh, we use a standarts of Omnitrope, Jintropin, Rastan, Genotropin and Norditropin. If the results of this test show that our substance is identical with the standards, it is allowed for the following tests.
3) a Blind comparison test - Passing this test we use an independent lab - SIL'verfarm. We select the substance and standarts in the same containers and send them for testing. Where what kind of material knows only special person from the laboratory conducting the tests. After receiving the results, if the substances in all samples showed the same results - we can prepare the documents (based on the findings of an independent laboratory), and consider your job done - we made the right substance with the desired purity.
It's great. But as an ordinary person to understand what his original work GH?
I think to understand good or bad gh you use you need to pass some tests. Because each test separately may not show the truth.
1) growth Hormone, Serum - an excellent test. But one can not be reliable. As the different organisms are different figures. Everyone has different metabolism and for reliable peak STG you need to pass several tests for several hours. As a confirmation of my words you can insert a link to the user manual Genotropin, section "PHARMACOKINETICS" https://www.accessdata.fda.gov/drugs...280s057lbl.pdf .
As you can read there - the spread of the results depends on many factors.
2) IGF-1 is a great test, but IGF can be "bind" IGFBP-3. IGFBP-3 is a peptide involved in the regulation of cell growth. It binds with the same affinity as IGF-1 and IGF-2. So it may be that IGF is low, while IGFBP-3 rolls.
For greater clarity, I can compare it how SHBG can "bind" testosterone and makes it inactive.
3) IGFBP-3 is also a great test, but as well as the other could not be reliable. As the cells of the liver GH should cause rise in IGF. For example if you have been taking oral AAS or any other drugs - it can greatly affect the results of the IGF. In fact any load on the liver may change the outcome of the IGF. For example for people who do not receive a high level of IGF in the treatment of growth hormone, used drug Increlex.
There is an opinion in the forums that 1IU GH should give +100 IGF-1 after 10-14 days, it seems to be true?
If so, I will start to use 15IU a day, I really want to see 1500 IGF :).
You need to understand that GH does not contain the IGF, it's just 191аа. IGF-1 is what should make your body more specifically the liver. This indicator is influenced by many factors - metabolism, mode, load on the liver health and susceptibility to the drug, and still a lot of factors.
Let's go back to the official instructions from Pfizer - they do not indicate possible values. Description of the IGF is reduced to a single phrase:
"During therapy, the dose should be decreased if required by the
occurrence of adverse events and/or serum IGF-I levels above the age - and gender-specific
normal range. Maintenance dosages vary considerably from person to person.".
If we translate this sentence into ordinary language it sounds like "who the fuck knows what will be there, everyone is different".
But how do you recommend to pass the tests?
I am a doctor and a scientist, I can't recommend people to conduct experiments on themselves without the supervision of specialists. But I can tell you like it was for me.
2 weeks before the test to stop using any other gh (that would not get "background"), any other drugs (if not prescribed by a physician) and started the diet and sleep.
The first day or 10IU.
The second day (Serum test) 1IU per 10 kg of body weight.
4 days 1IU per 10 kg of weight.
5 days 4IU
11 days, I would have passed the IGF-1 and IGFBP-3 with different time interval. And give them every day because I'm not important "snapshot" picture, I need to obtain the dynamics of the processes in my body.
Comment