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Anastrozole, tamoxifen, letrozole.

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  • Anastrozole, tamoxifen, letrozole.

    Should I use one of these with my next test/dbol cycle to prevent aromatization?

    Im thinking Anastrozole maybe, or is there something better? I need help with this..... All I really know about is clomid and nolvadex, not this stuff.

    Thanks.

  • #2
    Anastrozole only suppresses aromatise/estrogen. Whereas Nolvadex will block the estrogen from binding to the receptors and being a much better choice for you if I understand your question right.

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    • #3
      What about tamoxifen and letrozole?

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      • #4
        Nolvadex is tamofaxin and letrozole is an effective substance. You need to find exact amount or it can begin to mess up things like your lipid profile, libido and memory to name a couple. If you do use it, start with very low dosages and go from there. I'd probably just stick to Novladex.

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        • #5
          Thanks alot bro! Does everyone agree with this?

          Thanks again.;)

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          • #6
            Letrozple is the best choice ..it's strong enough to block up to 95% of the test converted keeps off the bloat and doesn't mess up your lipid profile ......you should have nolva ( tamoxifen ) in case you have a problem . If you use it while on cycle you will limit your gains. Everyone should have nolva on hand befor you start your cycle . We all hope never to need to use it.

            pompus is mistaken about the lipid profile with letro ...it is by far the best thing to us. Letro doesn't mess up the lipid profile the molecule is small enough to pass through the cell membrain thus blocking the water retention in the cell .......

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            • #7
              Originally posted by Golden_Muscle
              Thanks alot bro! Does everyone agree with this?

              Thanks again.;)
              no. nolvadex should only be kept on hand as a safeguard IMO. it is best to run a low dose of femara, or ldex through the duration of the cycle. read buyb12's post above.

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              • #8
                Thanks alot bros. I thought I may have had a new idea, but I will just stick to plain old nolva incase of problems.

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                • #9
                  good idea GM, Thats what i always do... It just simplifies things.

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                  • #10
                    IMHO best anti estrogen is aromasin...

                    Femara is great and very strong... but aromasin is almost as strong, and will not have the negative effect on lipid profiles that femara will.

                    Always have to keep health number 1 priority.

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                    • #11
                      I will agree that aromasin is by far the best, but also the more expenisve. Withe letrozole being so inexpensive and highly effective, I would go with either pill or liquid form, and run minimal dosages throughout cycle, the need for tomaxifen will be greatly reduced if used from the start

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                      • #12
                        Aromasin is MUCH stronger than letrozole from any literature Ive seen and experience. Obviously not mg per mg, but on a dose per dose it is.

                        Further, Letrozole has been shown while at effectively inhibiting aromatase, it also increases the aromatase enyme protien levels. Basically that means its works all fine and dandy, but once you come off it, your left in a state of high aromatase levels than you started with before you took the drug.

                        My personal combo

                        Aromasin + Nolvadex

                        Remeber Nolva is a SERM (Selective Estrogen Receptor Modulator) and can act agonisticly or antagonisticly depending on the tissue. Its great for the lipid profiles, as it acts agonisticly there.

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                        • #13
                          pompus is mistaken about the lipid profile with letro ...it is by far the best thing to us. Letro doesn't mess up the lipid profile
                          buyb12- you are WRONG. Pompous is clearly right on this! Letrozole is a very powerfull anti, if the right dose is used, it can block estrogen effectivley. If you go above that you may experience sides such as negative effects on your lipid profile, decreased libido, increased BP, and memory loss.

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                          • #14
                            I have never had sides from letro ..It is my prefered anti-eand I can use what ever I choose you know...I noticed a consideral loss in faty tissue while switching from armadex to letro.... As far as bp With the dbol who could tell what's causing it..it did goaway for me whenI stopped the dbol ...I don't I may be wrong thanks But letro for me

                            Letrozol is femera, which is an anti-estrogen.

                            Femara is 10-30x more effective than Arimidex in it's ability to pass thru the cell membrane of lipid (fat) cells and inhibit the activity of aromatase -- in other words, Femara is far superior in lowering estrogen levels in fat cells. This has two benefits for BBs; (1) Estrogen 'attracts' water, so less water retention (2) an average male BB is around 10%BF, that's a lot of lipid cells with aromatase inside them, so a substantial percentage of aromatase is left untouched by Arimidex due to it's poor ability to enter lipid cellsArimidex is approximately 80% effective at inhibiting aromatase, Femara is around 95-97%, Aromasin is 98-99%

                            notes:
                            1. J Clin Endocrinol Metab 2000 Jul;85(7):2370-7
                            2. J Steroid Biochem Mol Biol 1997 Nov-Dec;63(4-6):261-7

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                            • #15
                              aromasin(exemestane) is king.

                              strongest and wont hurt lipid profile or hurt libido.

                              ive been using it for a while now and really like it

                              also, if you use letro with tamoxifen, you need to use way more tamoxifen. letro makes nolva only 40% as effective as normal. so mixing the 2 isnt the best combo. yes adding nolva will still help stop gyno if the letro alone isnt enough, but youll be using much more nolva than normal.

                              again, exemestane doesnt have this problem.

                              and exemestane really is only a lil bit more money, its actually about the same price as many sell letro for.

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