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Originally posted by TrapsBrah
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Absolutely wrong. -
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That was not your original statement. You stated that cancer treatments kill more people than cancer itself. That is absolutely incorrect.Originally posted by TrapsBrah View PostComment
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Possible game changer.
Killer antibiotic now 25,000× more potent—and resistant to drug resistance
https://arstechnica.com/science/2017...ce/?comments=1Comment
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A new antibiotic uses sneaky tactics to kill drug-resistant superbugs
Drug-resistant bacteria have a new challenger.
A new molecule can kill deadly strains of common bacteria, such as Escherichia coli and Klebsiella pneumonia, that are resistant to most existing antibiotics. The drug works differently from currently available antibiotics, potentially making it harder for bacteria to develop resistance, researchers report September 12 in Nature.
Most antibiotics kill bacteria by weakening their cell wall or by preventing the production of certain proteins. But bacteria have, over time, evolved ways to circumvent these drugs. And as antibiotics are used frequently in both hospitals and agriculture, resistant bacterial strains are becoming more common. Infections with multidrug-resistant microbes are particularly worrisome, because they can turn usually easy-to-treat illnesses like strep throat or urinary tract infections into deadly ordeals.
The newly developed drug uses a different tactic. It inhibits a key enzyme in the cell membrane that helps the bacteria secrete proteins. “We're hitting a new target,” says study coauthor Peter Smith, an infectious disease researcher at Genentech, a biotech company based in South San Francisco, Calif. That means that strategies that bacteria use to evade existing antibiotics won’t work here, giving the molecule an edge.
When the enzyme is blocked, proteins build up in the cell membrane until the membrane bursts, ultimately killing the cell, says Floyd Romesberg, a chemist at the Scripps Research Institute in La Jolla, Calif., who wasn’t part of the study. Romesberg developed precursors to the antibiotic in his lab, but the new version is more effective, he says.
In tests in cultured cells and mice, the molecule killed off a variety of common gram-negative bacteria that cause infections in humans, including E. coli and Pseudomonas aeruginosa, and was also effective against gram-positive bacteria. Gram-negative bacteria, so called because of how they appear when stained for viewing under a microscope, are notoriously difficult to attack with antibiotics because of the microbes’ hard-to-penetrate cell membrane (SN: 6/10/17, p. 8). The drug also destroyed bacterial strains that are resistant to multiple kinds of antibiotics.
The molecule will need to go through additional testing and tweaking before it can be used in humans, Smith says. And it’s not a permanent solution to the growing problem of antibiotic resistance. Eventually, if molecules of this type are widely used as antibiotics, bacteria will evolve resistance, as they always do. But for now, it’s a step ahead.
https://www.sciencenews.org/article/...tant-superbugsComment
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Glad to see they are working on new
Forms of antibiotics.Comment
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Drug-resistant Salmonella Hits the U.S.
Oct. 17, 2018 -- At least 92 people in 29 states have been infected with a drug-resistant strain of salmonella, and raw chicken products appear to be the culprit, the CDC said Wednesday.
The agency thus far has not been able to identify a supplier responsible for the outbreak, which reaches from Hawaii to Maine. The CDC says laboratory evidence shows raw chicken products from a variety of sources were contaminated with SalmonellaInfantis.
Of the 92 who have been sickened, 21 have been hospitalized. No deaths have been reported.
Testing has shown that the strain of bacteria that has made people sick has been resistant to multiple antibiotics. This particular strain of salmonella has been found in both live chickens and raw chicken products, which the CDC says could mean it is “widespread in the chicken industry.”
The CDC and U.S. Department of Agriculture have shared the information with chicken industry officials.
The agency is not yet advising consumers to stop eating chicken but urges anyone who does to make sure it is properly cooked. The illnesses began in January, and the most recent case was confirmed in September.
Of the 92 cases, 11 were found in Pennsylvania, more than any other state. New York had 10, and Massachusetts and New Jersey both had nine cases. Other cases were in Alabama, California, Connecticut, Delaware, Florida, Georgia, Hawaii, Illinois, Indiana, Kentucky, Louisiana, Maine, Maryland, Michigan, Minnesota, Missouri, Nebraska, North Carolina, Ohio, Rhode Island, South Carolina, Tennessee, Texas, Virginia, and Washington.
Most people infected with salmonella get diarrhea, fever, and stomach cramps within 3 days of exposure. The illness usually lasts 4 to 7 days, and most people recover without treatment other than fluids, the CDC says.
In most cases, antibiotics are recommended only for patients who:
• Have a serious illness (such as severe diarrhea, high fever, bloodstream infection, or condition requiring hospitalization)
• Are considered at high risk for serious disease or complications (such as infants, adults over 65 years old, and people with weakened immune systems)
https://www.webmd.com/food-recipes/f...src=RSS_PUBLICComment
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