Milk thistle inhibits function of the androgen receptor.

[Androman]

Silymarin inhibits function of the androgen receptor by reducing nuclear localization of the receptor in the human prostate cancer cell line LNCaP. Read caption

https://instagram.com/p/BV7qZ0GF5NN/


Sent from my iPhone using Tapatalk

[Bouncer]

I'd like to see the actual study on this and read the details. Not that I don't believe it, I just like details. Do you have a link to the actual study or article?

[Androman]

I'd like to see the actual study on this and read the details. Not that I don't believe it, I just like details. Do you have a link to the actual study or article?

https://www.ncbi.nlm.nih.gov/m/pubmed/11532861/


Sent from my iPhone using Tapatalk

[BowHunter]

A few things to point out: They were talking about SM inhibiting AR activity in prostate cancer cell lines. This is GOOD news. Prostate cancer is very sensitive to androgens. Testosterone promotes existing prostate cancer. Also, "expression and steroid-binding ability of total AR were not affected by SM". This suggests that the AR inhibition is not systemic.

I can't really get any definitive information from just the abstract BUT what this implies to me is that milk thistle is beneficial in that it inhibits AR in the prostate (thus inhibiting the growth of prostate cancer) while not inhibiting AR body wide. There is ample anecdotal evidence that milk thistle does not inhibit gains from AAS as well.