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You'll guess where I'm going with this but essentially I've only just established the link http://www.medscape.com/viewarticle/442440_5 -
Old but good
Increase skeletal muscle & collagen synthesis AAS:
While injecting test increases protein synthesis by roughly 50 times, depending on dose and time, most bodybuilders forget that it will reduce collagen synthesis by more than 50% -- more like 80%, giving you the collagen synthesis rate of a senior citizen. Since collagen makes up tendons, bros are very prone to injury if they continue to lift very heavy, unless they cycle off T and let their collagen synthesis get back to normal. It's like having the skeletal muscle of a gorilla with the tendons of a very old man.
Winstrol increases collagen synthesis. It will give you bigger tendons. However, your body compensates for this by making them more brittle, weaker, and more prone to injury. I can't tell you how many bros work out anaerobically and become injured while on winstrol. Guys who lift in the 1-5 rep range while on winstrol, to baseball players who sprint all out from a stationary position -- winstrol should be the LAST drug they choose. Most of them like winstrol because they don't get the weight gain from it but it is very detrimental to bros who train for any sport anaerobically. Tendons tear easily on it.
Also, the drugs I mention increase collagen synthesis while also increasing collagen cross-linking integrity, making for a much stronger tendon.
Winstrol, on the other hand, will dramatically increase collagen syn, but ironically it decreases collagen cross-linking integrity, thus making a much weaker tendon.
You can plan a cycle of AAS which will increase collagen synthesis and skeletal muscle growth at the same time. The key is the drug(s) you choose.
Deca, Equipoise, Anavar, and Primobolan will ALL increase skeletal muscle while at the same time dramatically increase collagen syn and bone mass and density, leaving you with a substantially reduced chance of becoming injured than if you choose to use AAS like sus, cyp, or enth.
While testosterone will increase bone mass and density, even at supra-physiological levels, the result is weaker tendons due to inhibition of collagen syn.
To plan a cycle where the goal is to increase skeletal muscle mass/strength while at the same time increase joint/tendon/ligament strength, enough to keep up with the dramatic increase in skeletal muscle, you must choose drugs like Eq, Deca, Anavar, or Primo as the base of your cycle. Testosterone and its esters can be added to your cycle to keep levels within a 'normal' physiological range (ie, 100-200 mg/wk) but must not go above this. Since drugs like eq, deca, anavar and primo will reduce endogenous, natural levels of test, these levels may be maintained with exogenous test in the 100-200 mg/wk range. Test at this dose will not inhibit collagen syn, but paradoxically, will help increase it. It is when exogenous testosterone is used > 200 mg/wk that collagen syn is inhibited.
Deca @ 3 mg/kg a week(about 270 mg/wk for a 200 lb male) will increase procollagen III levels by 270% by week 2. Procollagen III is a primary indicator used to determine the rate of collagen syn. As you can see, deca is a very good drug at giving you everything you want -- an increase in collagen syn, an increase in skeletal muscle, and increases in bone mass and density. The one thing it does not give you is wood.
Primobolan, @ 5 mg/kg, will increase collagen synthesis by roughly 180% -- less than deca and equipoise but still substantial.
Equipoise @ 3 mg/kg will increase procollagen III by approximately 340% -- slightly better than deca.
Oxandrolone has over a hundred studies documenting its effectiveness at treating patients needing rapid increases in collagen syn to enhance healing.
These drugs have longer half-lives than most other AAS, so this should be considered when timing your post cycle Clomid use. Here they are:
Deca: 15 days Equipoise: 14 days Primobolan: 10.5 days
Anavar has a half-life of only 8 hours so it should not pose a problem.
GH is probably the most remarkable drug at increasing collagen synthesis. It increases collagen syn in a dose dependant manner -- the more you use, the more you will increase collagen syn. It has also demonstrated this ability in short and long term studies. From what I've read, hGH at 6 iu/day increased the collagen deposition rate by around 250% in damaged collagen structures. This result indicates that the increased biomechanical strength of wounds to collagen structures treated with biosynthetic human growth hormone was produced by an increased deposition of collagen in the collagen structures.
Eq, primo, anavar, and deca are all good -- they increase several biomakers of collagen syn -- ie, type III, II, I, procollagen markers. GH just seems to do so most dramatically.
Use of any of these drugs @ supra-physiological levels with a maintenance dose of test will increase collagen syn while at the same time increase skeletal muscle mass. Skeletal muscle mass gains will not be as dramatic as with large testosterone doses but you have to weigh the risk/reward basis for yourself. Also, these drugs do not satisfy the libido like testosterone, but that is not the point of this thread. It is only to demonstrate that you can increase skeletal muscle and collagen syn at the same time with certain AAS --- the decision is yoursComment
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And Bounce, before you jump in and say "I told you deca", that was based in its anti inflamatory
What I'm getting at here is the role certain aas could play in bolstering disk health insofar as type II collagen synthesis is a factor.Comment
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Is that what it's saying though? Looks to me like it's saying deca directly increases collagen not just anti inflammatory.
"Deca @ 3 mg/kg a week(about 270 mg/wk for a 200 lb male) will increase procollagen III levels by 270% by week 2. Procollagen III is a primary indicator used to determine the rate of collagen syn. As you can see, deca is a very good drug at giving you everything you want -- an increase in collagen syn, an increase in skeletal muscle, and increases in bone mass and density."
Mk-677 would be a good way to do it as well. Much cheaper than gh but does increase gh levels to that of something like 1-2iu per day of pharm grade HGH.Comment
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Exactly, it's the connection of collagen and disks I'm interested in.
It seems it could help mitigate degenerative diskComment
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Well in that case... BRO. I TOLD YOU DECAComment
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Aren't you on gh though?Comment
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On and off yeah but the gh is more for getting water in there and creating space. I'm gonna now ramp up primo to directly affect an improvement in disk health alongside everything else
This is yet another Mr I authentic strategy, some mainstream cunt will probably steal it for his own publicity.
Hope you all realise I'm guinee pigging and divulging my problems to share and possibly help others learn if it works rather than just sitting back and hording infoComment
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The article above says gh is the very best at collagen synthesis. Seems to me a combo of gh or mk-677 and deca is the best way to go. Primo isn't as good as deca according to article.Originally posted by Mr I View Post
Tb-500 for good measure. Add to that, 8-10 fish oil caps per day and I think you'll be feeling better in no time flat.
I'll join you. Already on the deca and fish oil. Testing out bpc-157 right now but so far noticing nothing. Gonna get some mk-677 and run 5 days on 2 days off starting next month. Blood work and studies show mk-677 is equal to 1-2 iu pharm grade gh per day. Not too bad. Has a long half life though and can cause gh bleed. Thus the need to come off 2 days per week.Comment
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Deca is dirty imo ill still with primo but high dose like 600mg pw
Not convinced on peptides except gh which bill try and stay constant withComment
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Dirty cause of progesterone? I used to say the same thing. Trick is to run it like me. Keep test much higher and estro in check and deca becomes a god send. No sides, all benefit.
My cycle just to give you and idea. Test gotta be much higher than deca or your fucked.
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Cool but 600mg primo alongside test should be good alsoComment
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I never ran primo always wanted to cause of Arnold and them guys running it. Think it's valuable in terms of physical results gains/cutting?Comment
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