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Nootripics - The "Smart Pill"

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  • Nootripics - The "Smart Pill"

    So i downloaded limitless yesterday and it got me thinking. Where in the fuck can i find myself some of the clear pill. I want to be Smarter, more clear minded and just more bad ass. So I did some research and found Nootropics

    Nootropic - Wikipedia, the free encyclopedia

    Nootropics (play /noʊ.əˈtrɒpɨks/ noh-ə-TROP-iks), also referred to as smart drugs, memory enhancers, neuro enhancers, cognitive enhancers, and intelligence enhancers, are drugs, supplements, nutraceuticals, and functional foods that improve mental functions such as cognition, memory, intelligence, motivation, attention, and concentration.[1][2] The word nootropic was coined in 1972[3][4] by the Romanian Dr. Corneliu E. Giurgea, derived from the Greek words νους nous, or "mind," and τρέπειν trepein meaning "to bend/turn". Nootropics are thought to work by altering the availability of the brain's supply of neurochemicals (neurotransmitters, enzymes, and hormones), by improving the brain's oxygen supply, or by stimulating nerve growth. However the efficacy of nootropic substances, in most cases, has not been conclusively determined. This is complicated by the difficulty of defining and quantifying cognition and intelligence.

    The more popular, and most affective, of these Nootrpics are

    Racetams

    The word nootropic was coined upon discovery of the effects of piracetam, developed in the 1960s.[27] Although piracetam is the most commonly taken nootropic,[27] there are many relatives in the family that have different potencies and side-effects. Studies of the racetams have revealed that these structurally similar compounds often act via different mechanisms. These other common racetams include pramiracetam, oxiracetam, and aniracetam. Their mechanisms of action are not fully understood, however, piracetam and aniracetam are known to act as positive allosteric modulators of AMPA receptors. They also appear to modulate acetylcholinergic systems.[28] Although aniracetam and nebracetam show affinity for muscarinic receptors, only nefiracetam shows it at the nanomolar range. Racetams have been called "pharmacologically safe" drugs.[10] Nefiracetam, however, shows much more serious health risks to males.[citation needed]

    Other substances sometimes classified as nootropics include hydergine, vinpocetine, bifemelane, huperzine A (cholinergic activator below), and dimethylaminoethanol (DMAE).[10]

    You can buy several of these compounds in bulk on amazaon by themselves to make your own blend but fuck that im no scientist!

    So I did some more snooping and found this product backed by joe fuckin rogan that i think i will be giving a try just to see if it works. Sure it wont work like in the movie but i could use some mental clarity and alertness.

    Onnitâ„¢ Labs, home Alpha Brainâ„¢, Shroomtechâ„¢, & New Moodâ„¢ Supplements – Onnit Labs

    Alpha Brain

    What do you guys think?

  • #2
    No bro all you need is Jins from 2003-2004. I thought everyone new that?

    Comment


    • #3
      Originally posted by ROCKETW19 View Post
      No bro all you need is Jins from 2003-2004. I thought everyone new that?
      :rofl::rofl::thumup:

      Comment


      • #4
        Before you drop any cash on this, read this article. Carefully and from beginning to end.

        Science-Based Medicine » Alpha Brain – What’s Wrong with the Supplement Industry

        Let me quote some of the key points:

        The site reviews all of the ingredients in Alpha-Brain explaining the science behind the claims – let’s look in detail at just one example, GPC choline, which is an essential nutrient and a precursor for the neurotransmitter acetylcholine. The site claims:

        "There is scientific evidence that proves that increased levels of acetylcholine in the body can dramatically increase memory and cognitive ability of men and women of all ages[1]"

        The concept here is not implausible, but also cannot be assumed, and is very common in the supplement industry. The idea is that a precursor of an important molecule in the body will increase the availability and therefore function of that molecule. That could be true, if availability of the precursor is the rate-limiting-step in the production and function of the molecule (emphasis is mine). Specifically in this case, is the nutritional availability of choline limiting the production and function of acetylcholine?

        Choline is an essential nutrient, so (as is true with all nutrients) in someone who is undernourished or with specific deficits in their diet, supplementing will help. But in someone with an adequate diet, there is no reason to assume that more will be better. Supplements treat deficiencies – but there is no reason to think that taking additional nutrients beyond the minimum necessary will have functional benefits.

        Comment


        • #5
          Bottom line: there is no evidence that choline in healthy individuals has any value to increase acetylcholine. This technique is pretty standard for the shysters in the supplement industry - for example, the people pushing glutamine. There is no evidence that glutamine does anything for healthy individuals. The fact that it most certainly helps burn victims recover has no bearing on its use for the average gym rat.

          Comment


          • #6
            Youre crushing my dreams here Scrum


            What is your insight on Nootropics in Genereal? Mainly the Racetams like pramiracetam, oxiracetam, and aniracetam, which I have read to be very popular with those trying to expand their mental capacity.

            Comment


            • #7
              Originally posted by COLOSSUS
              Youre crushing my dreams here Scrum

              What is your insight on Nootropics in Genereal? Mainly the Racetams like pramiracetam, oxiracetam, and aniracetam, which I have read to be very popular with those trying to expand their mental capacity.
              I think if it was even marginally as effective as claimed it would be a very hot topic and popular product flooding the market.

              Comment


              • #8
                The problem with the supplemnent industry is that ever since it was deregulated, there is zero credibility of any claims they make. In fact, they can claim just about anything they want as long as they don't claim they are treating a disease. Because that makes a supplemnt a drug in the eyes of the law and puts them under the purview of the FDA.

                So, as far as supplemnents are concerned, I would not believe anything that is claimed unless there are pubmed references that talk specifically about the efficacy of the drugs (whether you call them drugs or not, that's what they are) in the general humans that do not suffer from some specific illness or condition that would make such a treatment beneficial for them.

                If you carefully look at the literature, you will rapidly find that most of these claims are just bunk. There is usually either no evidence they work, or they may have been shown to have marginal promise in lab animals but have not been taken to the next level of clinical trials.

                And why do they not do the next level clinical trials to validate their efficacy? The answer is - why bother? Clinical trials are a lose-lose proposition for the supplement companies. You can claim pretty much anything you want short of saying your product cures a disease right now without a clinical trial. What's a trial going to show? That it doesn't work! The system is set up to where there is ZERO incentive for the supplement companies to do any rigorous testing. The only thing you have to do is to make sure you are not going to kill or maim anyone and you are good to go. It is really a national disgrace but we can thank well-entrenched fat cats like Orrin Hatch for the current status quo.

                Comment


                • #9
                  well in that case i wont go for the brand, jeez.


                  Ill just order some Piracetam and Choline online :thumup:

                  Amazon.com: Piracetam Powder by SNS 1GRAM (1000MG) per serving (500 servings) Serious Nutrition Solutions: Health & Personal Care

                  Comment


                  • #10
                    Originally posted by COLOSSUS View Post
                    well in that case i wont go for the brand, jeez.


                    Ill just order some Piracetam and Choline online :thumup:

                    Amazon.com: Piracetam Powder by SNS 1GRAM (1000MG) per serving (500 servings) Serious Nutrition Solutions: Health & Personal Care


                    Start a log :D

                    Comment


                    • #11
                      My personal opinion is that you are wasting your money, but of course, the decision is yours.

                      Comment


                      • #12
                        Originally posted by FitnessBrat View Post
                        Start a log :D
                        Maybe i will!

                        Originally posted by Scrumhalf View Post
                        My personal opinion is that you are wasting your money, but of course, the decision is yours.
                        Its cool. I got some time on my hands. I could use for some mental clarity so why not give it a try.

                        as of now i have been taking True Focus and True Calm from NowFoods

                        its alright. i only take it now when im feeling "low".


                        Also taking valerian root at night

                        Comment


                        • #13
                          Alpha brain is shit. I bought a bottle just to try out, and they also have a money back guarantee. Wrote them and explained that I did not like them and they promptly refunded my money.

                          Comment


                          • #14
                            Originally posted by Scrumhalf View Post
                            Bottom line: there is no evidence that choline in healthy individuals has any value to increase acetylcholine. This technique is pretty standard for the shysters in the supplement industry - for example, the people pushing glutamine. There is no evidence that glutamine does anything for healthy individuals. The fact that it most certainly helps burn victims recover has no bearing on its use for the average gym rat.
                            Exactly.

                            Comment


                            • #15
                              Originally posted by Scrumhalf View Post
                              My personal opinion is that you are wasting your money, but of course, the decision is yours.
                              Agreed. Let us know how that turns out for you, and I'm not being a smart ass lol I really would like to know. Reading and studying something is a good way to get smarter, but that means you have to work to get it and who wants to do that lol

                              Comment

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