INSUBOLIC : IGF-1 (Recombinant Human IGF-1)

[johnrico022117]

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[Freak]

In the past i use alot IGF Lr3 but nothing comes even close to this Insubolic . I have the most insane pumps of my life .

[roidsource]

Good evening Ladies and Gents,

I often spend time researching scientific data on rhGH and rhIGF-1 combination therapy.
Came across this study today :
https://pubmed.ncbi.nlm.nih.gov/8967666/
" Group 3 (IGF-1+HGH) had the greatest changes in lean body mass (mean +/- SE, 3.2 +/- 0.59 kg; P < 0.001)"
This feedback supports the studies you can easily find by googling : "rhGH and rhIGF-1 Combination Therapy" If you find something interesting, please, share.
...................
Hey RS,

I’m really liking this Qtropin and Insubolic stack! This is quality clean stuff bro. Now I see why it’s $140 per 5ml. The packet was still cold when I opened it to. That’s the first time I’ve had it come with the cold packet. That was legit.

I usually pay $245 for 280 iu. But I have to take 10 iu a day to get same effects as what I get when I take 6 iu’s of Qtropin and 3 of Insubolic pre workout. It’s still 9 iu’s of growth but the two together are much stronger and produce much cleaner results. I not only feel better but I look better to.

I’m glad I found you bro. This is a game changer for me. I haven’t had legit pharma grade like hgh for over 2 years.

..................

RS

[roidsource]

As a side note, there're people who use HGH and feel great : no water retention (BTW, fluids can be retained in many organs, including prostate), no increased HR, normal BG etc. But there're some, I'd say many, who want to benefit from IGF-1, but the side effect outweigh the benefits. With IGF-1 I have 0 water retention, my HR is normal, I don't feel sleepy all day, my endurance is better. With HGH + IGF-1 you get the best of both meds, just look at the chart above, the combo has been clinically studied and proven to be synergistic.

[roidsource]

Okay RS, I have a question about the insubolic. (I am green in this department so bare with me.but trying to learn) when taking HGH, it converts to IGF-1 in the liver after injecting, so why take IGF-1 while taking HGH at the same time? I'm sure there is a purpose but help me understand. Thanks in advance. roidsource

HGH therapy reduce Insulin sensitivity, IGF-1 enhance insulin sensitivity, both medications promote protein anabolism, lipolysis and lipid oxidation and reduce protein oxidation by different mechanism. The study suggests that combined use of IGF-1 and HGH has great potential and synergistic effect.

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Insulin-like growth factor-I ( IGF-I) is considered to be the mediator of the growth-promoting effects of growth hormone ( GH). The metabolic effects of these two hormones, however, are different. Whereas GH treatment leads to elevated insulin and glucose levels, reduced insulin sensitivity, and impaired glucose tolerance, IGF-1 treatment leads to reduced insulin and GH levels and enhanced Insulin sensitivity. IGF-I may, therefore, not only be the mediator of the growth-promoting effects of GH but also a modulator of the effects of GH on insulin action and glucose metabolism. To study the influence of GH and IGF-I on substrate metabolism and insulin sensitivity (assessed by euglycemic, hyper-insulinemic clamping combined with indirect calorimetry and glucose tracer infusion), we have treat. eight GH-deficient adults with GH (2 IU/m. daily subcutaneously fs.c.)), 1GF-1 (10 mcg/kg • h s.c.), or both hormones together for 7 d, respectively, and compared the effects of these treatment regimens
with a control phase. Our findings suggest that (a) both GH and IGF-I promote lipolysis and lipid oxidation, albeit by different mechanisms; (b ) treatment with either hormone is followed by enhanced energy expenditure and reduced protein oxidation; and (e) IGF-I reverses the insulin resistance induced by GH. (J. Clin. Invest. 1994.94:1126-1133.)




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Effects of GH and IGF-1 on protein oxidation.
Reduction of protein oxidation, i.e., of proteolysis, was observed under IGF-I as well as GH treatment. When both hormones were given together, the effects of IGF-I and GH were additive. These findimgs support those of a previous report also showing that anabolism may be stimulated to a greater extent by treatment with GH and IGF-I together than by either hormone alone (40). Moreover, insulin-like properties of IGF-I 30) and the fact that IGF-I increases insulin sensitivity of skeletal muscle may allow us to preserve normal glucose tolerance when GH and IGF-I stimulate protein anabolism in a concerted fashion.

In conclusion, our results show that IGF-I per se is a potent anticatabolic agent (as in regard to protein metabolism) leading by way of partial inhibition of insulin secretion to increased lipolysis and fat oxidation. These effects of IGF-I are indepenedent of the inhibitory effect on growth hormone secretion. All these effects of IGF-1 are, however, synergistic to those of GH, which stimulates lipolysis and possibly protein anabolism through mechanisms different from those of IGF-1. In the case of simultaneous administration of GH and IGF-1, insulin levels lie between those attained by IGF-I treatment alone and those observed during GH treatment. Since insulin is an important anabolic hormone (41), it is conceivable that in situations of severe catabolism a combination of GH and IGF-I together will turn out to give the best results with regard to anticatabolism and anabolism (40).


www.ncbi.nlm.nih.gov/pmc/articles/PMC295178/?page=1

[roidsource]

Test E - 500mg/wk
Primo E 500mg/wk
Qtropin HGH - 4iu daily
Insubolic RH-IGF-1 200mcg daily preworkout

Cardio - 15min HIIT a few times a week just to keep heart and glucose healthy.
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Cycle started Dec 28th, starting weight 211,5lb, as of Feb 8th : 224.2lbs = + 13 lb.

P.S. From what I see, with 13 lb added in 6 weeks, the waist got tighter, that's exactly what the athlete said as well: "I noticed my pants felt looser than prior in the waist. Thought I'd be down for the week in weight and would need to raise calories. Instead I was up 1.5lbs"

IGF-1 is helping to gain leaner mass here, especially, seeing that the athlete does 15 min cardio just a few times a week.

Progressing with lower AAS dosages. That's another benefit of using RH IGF-1. Instead of increasing your AAS dosages, you may just add 200 mcg/day.

Lower HGH dosages or no HGH at all. Lots of athletes use 6 IU's of HGH +, + slin. HGH at high dosage almost guarantees water retention, increased blood glucose (lowered insulin sensitivity). Most athletes can run HGH at lower dosages, and avoid using slin.

RS

[Marshall1019]

Okay RS, I have a question about the insubolic. (I am green in this department so bare with me.but trying to learn) when taking HGH, it converts to IGF-1 in the liver after injecting, so why take IGF-1 while taking HGH at the same time? I'm sure there is a purpose but help me understand. Thanks in advance. roidsource

[roidsource]

[roidsource]

A very interesting observation from our client on how the Insubolic IGF-1 helps reduce sides of Trenbolone

Thanks for your time and the Insub+gh is amazing btw. It has literally reduced the sides of a TMP cycle to almost nothing, I sleep 8 hours a night and am eating like a horse right up to bed and no night sweats. I was on cycle two weeks before I got the insub and was sweating like a whore in church every night so again weeks later still having the same positive results just fyi. I Have lost about 8lbs and gained about 12 of what seems like really solid muscle that is here to stay, no water ret. Biceps have gone up 1.5" before WO and almost 3" PWO pump. I honestly hurt some days to finish. Anyway enough of my ramble, just wanted to give some honest feedback.
Appreciate your honest business and have sent some old friends your way and will continue. They have the same feedback btw, love insub.

[roidsource]

There's a clinical study done on this combo :

www.ncbi.nlm.nih.gov/pmc/articles/PMC295178/?page=1
Check out the panel on Page 1131

C-peptide and Insulin levels are significantly lower in the IGF-1 + HGH group vs HGH only.

https://roidsource.me/forum/oral-ste...-1-qtropin-hgh

[roidsource]

[roidsource]

[roidsource]

This is the most recent HPLC test on Recombinant Human IGF-1 (Insubolic)


And it's bioactivity test.


Insubolic IGF-1 is bioidentical to the IGF-1 produced by our body. It can be run for months and Qore Pharm makes it affordable. You no longer need to experiment with research grade chemicals, such as LR3/DES. Use the real hormone, which is native to your body.
The products we carry are not just pure, but also highly bioactive.

RS

[roidsource]

We often hear, why IGF-1 LR3/DES is available everywhere while IGF-1 (Recombinant Human aka Mecasermin, Increlex) is not.

One of the main reasons is how the substances are produced.




This machine - Peptide Synthesizer is used to create(assemble) peptides from amino acid residue.






Proteins (HGH/IGF-1) are not assembled from amino acids residue by a chemical process, but assembled inside the cell or eukaryotes or prokaryotes, which is identical to the proteins created by our own cells.




The manufacturing process of IGF-1/HGH involves cultivation, purification etc, so it becomes identical to our endogenous IGF-1/HGH.




When you inject IGF-1 (Insubolic, Recombinant Human IGF-1) you inject the substance that's naturally produced by your body, which won't provoke an immune response in the body.




RS

[roidsource]

This is Insubolic Bioactivity test. The Insubolic IGF-1 has been added into a tube with live cell culture.