"Cleaning out the receptors"

[RollPlayer]

Can someone explain exactly what this means, and how to go about doing it properly? I have heard the receptors get 'filled up' and inhibit gains. What are the receptors?

If this is a stupid question just point me in the direction of some decent information. Thanks in advance.

[RollPlayer]

No answers????

Come on guys... There are more people on this board than most that I've been to and nobody can give me an answer or point me in the right direction to find it myself? I'll have to continue searching. Thanks.

[The B]

I have never heard of "cleaning out" receptor sites. But, that doesn't mean it is not possible. Just like every chemical system in your body, hormones have receptor sites. They are designed to only accept things with a certain chemical or molecular make up. This makes it so nerve impulses and hormone reactions don't get mixed up. I DO know that receptor sites can become desensitized over time, but I don't know of any way to reverse this. I'm sure Skyefire can explain this much better. You can take a look at most anatomy or chemistry textbooks for a more in depth description....it shouldn't be hard to find. I hope this helped a little bit!

[Bouncer]

The receptor theory has been proven bunk. We have millions of new receptors every minute.

[RollPlayer]

For those who might not know about receptors....
I found this at Intense-Training.com

Cleaning Receptors

--------------------------------------------------------------------------------

Written by Trevor Smith.
I do not necessarily agree with the product plug at the end and would also offer up Clen as a viable alternative to DNP or T3
~~~~~~~~~


A lot has been said in regards to clearing the receptors and I thought now would be a good time to delve into this
subject and simplify things.

Basically, one must view the receptor sites as parking spaces.

Envision a slew of parking spaces that are all empty. Now we are going to call these parking spaces your receptor
sites and we shall call steroids the cars. Now I want you to imagine one of those old 1950's style drive up
hamburger stands where the girls come up in roller skates and take your order. Typically one would order a burger,
fries and a coke--ah the food of the gods--the waitress would take the order, go bring the information to the
cook, who would in-turn make the food and the waitress would then bring the food to you and you would then
begin eating which is the whole reason you came to the hamburger stand in the first place.

I think everyone can easily understand that. Which means everyone can easily understand all they need to know
about the receptor sites because they do the exact same thing. We will keep with this hamburger stand model and
explain what happens when you inject steroids and they begin to go to work.

Remember how I said steroids were like the cars and the parking spaces were like the receptor sites? Well it is
basically that simple. When you inject testosterone or any one of it's anabolic or androgenic derivatives, you are
sending a whole slew of "cars" into your system. Now these "cars" are on a mission--just like you would be if you
were hungry and heading to a hamburger stand. They have orders to place with the cells, but before they can
place them they must first find a parking space.

Now let's say you have never used steroids before. If this were the case, it would be very much like a hamburger
stand that was having a grand opening....lots and lots of empty parking spaces waiting for cars to fill them up and
place their orders. The steroids (cars) enter the system and come to a brand new hamburger stand called your
cells. Now these cells have never previously been open to the boat-load of anabolics that are now present in the
system because they previously only dealt with what your body naturally produced. However, there are lots of
extra parking spaces that can be utilized and so the steroids park themselves into these spaces.

Once they are parked a "waitress" called CYCLICl AMP literally crosses the cellular membrane which is totally
impenetrably to anything else and takes the order from the steroid. The order is quite simple: Build More Muscle!!

The "waitress" then crosses back through the cellular membrane and brings the order to the "cook" called the
Nucleus who begins to fill it by ordering its helpers called Ribosomes to produce muscle protein.. Now different
steroids will have slightly different orders in that some may have a bigger order for the cook to fill--such as
testosterone. The thing you have to realize is that a lot of times, after the order is placed, the steroid does not
necessarily leave the parking space and make it available to other steroids.....it will often sit in the parking space
even though it is no longer sending orders to the "waitress" to bring to the "cook", and this is where the problem of
"DOWN-REGULATION" comes in. You see even if you send in more and more fresh new "cars" to occupy the
receptor spaces, if they are already taken up by old "dead cars" you are **** out of luck.....

This is why you do not continually grow by injecting bigger and bigger doses of steroids. THERE ARE A LIMITED
NUMBER OF PARKING SPACES. Now it would not be so bad if all the parking spaces were taken by "cars" that were
sending orders to the cook, because that is when you grow. The problem is when there are "cars" that are no
longer sending orders and on top of that have dead batteries which is preventing them from exiting the receptors
parking space.

This is what the whole point of this article is....TOWING AWAY ALL THE DEAD "CARS" FROM THE RECEPTOR SITES
PARKING SPACES AS TO FREE THEM UP FOR NEW, FRESH, HUNGRY "CARS" TO OCCUPY THEM...This will result in
new muscle mass!

O.K. Trevor, I am with you so far, but what the **** can I do about it?

The answer is ...PLENTY!

First and foremost, is to plan sensible courses. This is why I am an advocate of short courses designed in such a
fashion as to have all drugs out of the system by the end of the cycle and then allow for a 3-4 week off time in
which you are totally clean. If you stay on these monster 4-6 month courses, you just wind up screwing yourself
and requiring that much longer of an off period. The longer you are on, the more the body recognizes that there is
"too much" in the system and will begin to take counter measures. And the longer you are on, the more "dead cars"
you will have sitting in the receptor parking spaces which means NO MORE GROWING!

Now with this in mind, how can we help get the cars out of there?

Well WE actually cannot, but the body can and will. Basically as time goes by, the body will free up the parking
spaces just like a tow truck would remove a dead car from a parking space. However, you are at the mercy of time
in this situation which is why it is important to utilize short courses that will cause less disturbance in the system,
less "dead cars" in the receptor spaces and therefore less time needed for the body to remove them and free up
the spaces.

That being said, it should be noted that even short course will pile up "dead cars" after a while and you should give
yourself an extended clean out of 2 months at least once a year.

But Trevor, isn't there anything I can do to help speed the process?

Once again the answer is yes!

You can help speed the process up dramatically by increasing your metabolic rate...Speeding up the metabolic rate
is akin to hiring extra tow trucks to clear out all those "dead cars" that are occupying the receptor sites!

Have you ever know a person who was much, much fatter than you and yet ate half as much?

These poor bastards think they were given the genetic shaft and try every diet fad imaginable only to stay fat.
Their problem no longer lies in their eating habits--which is ironic--; it lies in their metabolism, which basically was
shut down due to the excess eating and lack of exercise that got them fat in the first place. Once you understand
this, you can easily control your weight for the rest of your life. But what the **** does this have to due with
steroid receptor sites?

EVERYTHING!

The same thing I would prescribe someone whose metabolism has shut down due to obesity, is the same thing I
would prescribe someone who's receptor sites are all clogged and is no longer making progress....INCREASE THE
METABOLIC RATE!!

Below I will outline a few ways this can be achieved in the constraints of a 4 week Receptor Clearing Cycle follwing
the completion of a Muscle Building Course using anabolics:

Diet: I suggest cutting back 300 calories below maintenance per day during a 4 week off time from your anabolic
regime...I also suggest eating 6-8 small meals spread out from early morning to late at night. The higher the
number of meals you eat, the more your body has to go to work and break down the food which causes the
metabolic rate to increase.

Aerobics: Yet another tool in the battle to increase the metabolism, I would suggest low level aerobics 5 times per
week 30 minutes per session.

Pharmacology: It is important that one does not have ANY anabolics that are active in the system during this time
period.....make sure that you have had a good 4 weeks since your last shot of long acting compound before you
embark on this 4 week receptor clearing cycle....otherwise you are wasting your ****ing time! That being said, I
would suggest the use of the following compounds to help accelerate the Receptor Clearing Process:

1. D.N.P. -- Understand that this is a ****ing vicious poison and a component in T.N.T., and I do not suggest it's
use at all, but to be fair I must admit that NOTHING can raise the metabolic rate like D.N.P. can. Because this is
well known, there are many people that will want to try it...This being the case, D.N.P. should only be used in the
following manner during this course: 3 days on, 4 days off at a dose of 4mg per kilogram of bodyweight taken
before bed----have plenty of towels around and a fan to keep you cool!
2. Cytomel--T3 is another booster of metabolic rate which is why the fitness models live on this stuff...it keeps
you engines running high and burns the fat right off....In this case, we are more concerned with the fact that it
increases the metabolic rate. Suggested use is 75mcg -100mcg 5 days on 2 days off for the 4 week course

3. B.M.R. 10--I know, I know shameless plug right...well I don't care, in the past 3 weeks since this product has
been released I have people calling me and emailing me telling me that this product blows the doors off every other
thermogenic including, E/C/A, Clenbuterol and Cytomel, and Tenuate.....People actually think I put D.N.P. in this
product. Trust me I did not, but I did formulate a product with 11 Basil Metabolic Rate increasing compounds that
will make you hotter than an oven and melt the fat right off you. Again in this course we are more concerned with
the metabolic increase this product will cause. Why hasn't anyone else come up with this formula...#1 All the other
companies market to the general public which causes them water down there products #2 it is too expensive for
their profit minded companies to justify it's production #3 They are not bodybuilders, I am and I know what works
and what doesn not.

Doses: On the days you are NOT using D.N.P. have 4 caps before each of the first 5 meals.

* If you do not wish to use D.N.P.---which I think is the smarter approach as it is very dangerous---you can
simply use the B.M.R. 10 on the days that you would be using D.N.P. In my opinion this is smarter, safer and will be
just as effective.

There you have it...a brief simple lesson on your receptors and how you might go about keeping them free and
clear so you can continue to Grow, Grow, Grow

[house1]

Androgen receptors have been shown to up-regulate in response to administration of exogenous androgens. There’s no such thing as "plugging up" or "cleaning out" a receptor. It’s a matter of increasing (up-regulating) or decreasing (down-regulating) androgen receptor expression and, going further upstream, increasing or decreasing AR mRNA expression.

[RollPlayer]

Originally posted by THE BOUNCER
The receptor theory has been proven bunk. We have millions of new receptors every minute.

So it is unneccessary to 'clean the receptors'? Would normal PCT followed by a determined "OFF" time be adequate then?

[Bouncer]

Originally posted by house1
Androgen receptors have been shown to up-regulate in response to administration of exogenous androgens. There’s no such thing as "plugging up" or "cleaning out" a receptor. It’s a matter of increasing (up-regulating) or decreasing (down-regulating) androgen receptor expression and, going further upstream, increasing or decreasing AR mRNA expression.

exactlly. the body simply needs more to grow.

[RollPlayer]

Also, is Clen okay to use during PCT? or between cycles?

[Bouncer]

Originally posted by RollPlayer
So it is unneccessary to 'clean the receptors'? Would normal PCT followed by a determined "OFF" time be adequate then?

You cant clean a receptor so to speak. your body will eventually just stop growing on 500mgs of test. no matter what you try to do to the receptors, your body wont grow until you up the dose a bit.

[RollPlayer]

Thanks guys. I'm heading into PCT after my first cycle and was just curious. Appreciated.

[canadagold]

I think with Trevors analogy he should have put in that when a restaurant gets so busy that it can't hold all the cars the owner will then buy more parking spaces so that more cars can park. . .or in other words more receptors proliferate and therefore more androgens can be taken to fill them and that equals more growth. . .

[uuugeboy]

Rollplayer you're not too far off. If everyone that disputes rollplayer's first post would simply read the first twenty pages of BTPB you'd have a much greater understanding that receptors can not only be cleaned out but at a much faster rate than letting the body naturally cleanse itself. This is not only backed up in the book, the book also has a complete works sited/bibliograpy which posts the exact scientific article. Of course the example in the book may kill a normal human, there are safer ways to accomplish it now. If you'd like to post any rebuttles or arguments which I can sense coming from the posts I've read above, please read the first part of the book before taking a solid stance and flaming the shit out of me.

[thedon768]

Uuugeboy

Hi Uuugeboy I have totally screwed myself abusing steroids over the years I havnt been able to keep a pound of it am and half a stone below my usual weight now and steroids don't have any affect on me what so ever now, you say I can sort out my receptors faster than once thought, how would you recommend I do this? And have you seen first hand this route work for other people before? Thanks

[Bouncer]

Hi Uuugeboy I have totally screwed myself abusing steroids over the years I havnt been able to keep a pound of it am and half a stone below my usual weight now and steroids don't have any affect on me what so ever now, you say I can sort out my receptors faster than once thought, how would you recommend I do this? And have you seen first hand this route work for other people before? Thanks

Your gear is either fake or you need to up the dose. Train heavy and hard, feed your muscles quality cals and you'll get results. May need to switch things up. Different compounds etc.. Switch from long acting test to short acting test, add compounds, remove compounds, mix things up bro.

If you've been on on 500mgs test e for 10 years your not gonna get any new results.