I'm glad to find out about Letro...but what about 6-oxo? I think the chemical name is androstenetrione...I've been using that for years and it works great for boosting testosterone. I'm not a body-builder, though, just wanted more testosterone and less estrogen.
My testosterone levels are high and estrogen low using the 6-oxo, and I don't have a gyno problem...the 6-oxo can be hard to get, so I'm worried about not being able to get it. Is there any reason Letro would be better? Letro is a synthetic drug, with corresponding strange metabolites, no doubt, whereas androstenetrione is a form of hormone, it just binds irreversibly to aromatase without activating aromatase, so it kills the conversion of testosterone to estrogen very effectively.
By the way, for those how might now know, testosterone does not feed back onto the pituitary...only estrogen. So, if you supplement with testosterone without blocking the conversion to estrogen, you'll suppress the testicles and they'll shrink. Androstenetrione raises testosterone levels by lowering estrogen levels (by blocking aromatase) and thus tricking the pituitary into thinking testosterone is too low (because it's assuming there isn't enough testosterone to convert to enough estrogen), so the pituitary then puts out (I forget the hormone) the factor that stimulates the testicles to make more testosterone.
I'd just rather use a compound closer to a natural hormone (androstenetrione) than a synthetic drug (Letro), but was surprised to not see androstenetrione mentioned in the writeup that started this thread.
Feedback? Comments? Enlightenment?
My testosterone levels are high and estrogen low using the 6-oxo, and I don't have a gyno problem...the 6-oxo can be hard to get, so I'm worried about not being able to get it. Is there any reason Letro would be better? Letro is a synthetic drug, with corresponding strange metabolites, no doubt, whereas androstenetrione is a form of hormone, it just binds irreversibly to aromatase without activating aromatase, so it kills the conversion of testosterone to estrogen very effectively.
By the way, for those how might now know, testosterone does not feed back onto the pituitary...only estrogen. So, if you supplement with testosterone without blocking the conversion to estrogen, you'll suppress the testicles and they'll shrink. Androstenetrione raises testosterone levels by lowering estrogen levels (by blocking aromatase) and thus tricking the pituitary into thinking testosterone is too low (because it's assuming there isn't enough testosterone to convert to enough estrogen), so the pituitary then puts out (I forget the hormone) the factor that stimulates the testicles to make more testosterone.
I'd just rather use a compound closer to a natural hormone (androstenetrione) than a synthetic drug (Letro), but was surprised to not see androstenetrione mentioned in the writeup that started this thread.
Feedback? Comments? Enlightenment?

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