A new study suggests that estrogen is essential to keep neurons communicating and memories being made.
This shows at estrogen has a clear role in synaptic plasticity, how neurons communicate and in memory. It was known that aromatase, the enzyme that converts testosterone to estrogen, was made in the brain’s hippocampus and cerebral cortex in a variety of species that includes humans—and that all species tested have memory deficits when aromatase is blocked.
Knockout mice can't remember as well as normal mice. And clinical patients who take an aromatase inhibitor for estrogen-dependent breast cancer have reported memory problems.
The findings implicate neuron-derived estrogen as a novel neuromodulator, a critical messenger that neurons rely upon to communicate with others, which is essential to key functions such as memory and cognition.
https://www.techexplorist.com/estrog...icating/21149/
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